3D breath-held cardiac function with projection reconstruction in steady state free precession validated using 2D cine MRI

3D breath-held cardiac function with projection reconstruction in steady state free precession validated using 2D cine MRI
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DOI:
10.1002/jmri.20145
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发表时间:
2004-09-01
影响因子:
4.4
通讯作者:
Arai, AE
Arai, AE
中科院分区:
医学2区
文献类型:
--
作者:
Peters, DC;Ennis, DB;Arai, AE

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目的:研制并验证一种三维单次屏气。与二维(2D)多层傅立叶(Cartesian)变换(FT)SSFP方法相比,投影重建(PR)、平衡稳态自由进动(SSFP)方法用于心功能评估。材料和方法:3D PR SSFP序列使用x-y平面的投影和z的分区,提供70-80ms的时间分辨率和1.7x1.7x8-10 mm的24次心跳屏气。结果:血液和心肌的平均信噪比(SNR)分别为114和42(213)和59和21(3D)。Bland-Altman分析比较二维和三维射血分数(EF)、左室舒张末期容量(LVEDV)和收缩末期容量(LVESV)。而舒张末心肌质量(LVEDM)提供的BIST+/-2SD分别为0.6%+/-7.7%、5.9mL+/-20mL、-2.8mL+/-12mL。LVEDM为-0.61g+/-13g。LVEDM和LVEV的3D观察者间变异性大于2D。结论:在单次屏气中,3D PR方法提供的信息与标准2D FT方法相当,后者使用10-12个屏气。
Purpose: To develop and validate a three-dimensional (3D) single breath-hold. projection reconstruction (PR), balanced steady state free precession (SSFP) method for cardiac function evaluation against a two-dimensional (2D) multislice Fourier (Cartesian) transform (FT) SSFP method.Materials and Methods: The 3D PR SSFP sequence used projections in the x-y plane and partitions in z, providing 70 - 80 msec temporal resolution and 1.7 x 1.7 x 8 - 10 mm in a 24-heartbeat breath hold. A total of 10 volunteers were imaged with both methods, and the measurements of global cardiac function were compared.Results: Mean signal-to-noise ratios (SNRs) for the blood and myocardium were 114 and 42 (213) and 59 and 21 (3D). Bland-Altman analysis comparing the 2D and 3D ejection fraction (EF), left ventricular end diastolic volume (LVEDV) and end systolic volume (LVESV). and end diastolic myocardial mass (LVEDM) provided values of bias +/-2 SD of 0.6% +/- 7.7% for LVEF, 5.9 mL +/- 20 mL for LVEDV, -2.8 mL +/- 12 mL for LVESV. and -0.61 g +/- 13 g for LVEDM. 3D interobserver variability was greater than 2D for LVEDM and LVESV.Conclusion: In a single breath hold, the 3D PR method provides comparable information to the standard 2D FT method, which employs 10-12 breath holds.