High-field diffusion MR histology: image-based correction of eddy-current ghosts in diffusion-weighted rapid acquisition with relaxation enhancement (DW-RARE).
High-field diffusion MR histology: image-based correction of eddy-current ghosts in diffusion-weighted rapid acquisition with relaxation enhancement (DW-RARE).
复制标题
高场扩散 MR 组织学：在具有松弛增强功能的扩散加权快速采集中基于图像对涡流鬼影进行校正 (DW-RARE)。
DOI：
10.1002/mrm.21876
复制
发表时间：
2009
影响因子：
3.3
通讯作者：
Frank,LawrenceR
中科院分区：
文献类型：
--
作者：
Tyszka,JMichael;Frank,LawrenceR
High‐resolution, diffusion‐weighted (DW) MR microscopy is gaining increasing acceptance as a nondestructive histological tool for the study of fixed tissue samples. Spin‐echo sequences are popular for high‐field diffusion imaging due to their high tolerance toB0field inhomogeneities. Volumetric DW rapid acquisition with relaxation enhancement (DW‐RARE) currently offers the best tradeoff between imaging efficiency and image quality, but is relatively sensitive to residual eddy‐current effects on the echo train phase, resulting in encoding direction‐dependent ghosting in the DW images. We introduce two efficient, image‐based phase corrections for ghost artifact reduction in DW‐RARE of fixed tissue samples, neither of which require navigator echo acquisition. Both methods rely on the phase difference ink‐space between the unweighted reference image and a given DW image and assume a constant, per‐echo phase error arising from residual eddy‐current effects in the absence of sample motion. Significant qualitative and quantitative ghost artifact reductions are demonstrated for individual DW and calculated diffusion tensor images. Magn Reson Med, 2009. © 2008 Wiley‐Liss, Inc.
