Relation of C-6 glial cells in culture to myelin.

Relation of C-6 glial cells in culture to myelin.
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培养中的 C-6 神经胶质细胞与髓磷脂的关系。

DOI:
10.1042/bj1520701
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发表时间:
1975
期刊:
The Biochemical journal
影响因子:
--
通讯作者:
C. Agrawal
C. Agrawal
中科院分区:
--
文献类型:
--
作者:
Joseph J. Volpe;Karen Fujimoto;J. Marasa;Harish;C. Agrawal

文献摘要

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C-6胶质细胞的质膜中富含髓磷脂特有的2′:3′-环核苷酸3′-磷酸水解酶,此外,还含有蛋白脂质蛋白和两种基本蛋白,它们的电泳迁移率与髓磷脂中各自发现的蛋白相同。这些数据表明C-6细胞具有产生髓磷脂的胶质细胞和星形胶质细胞的特征。
C-6 glial cells were shown to contain enriched in their plasma membranes an enzyme, 2':3'-cyclic nucleotide 3'-phosphohydrolase, characteristic of myelin, and, in addition, proteolipid protein and two basic proteins that are identical in their electrophoretic mobilities with the respective proteins found in myelin. The data indicate that C-6 cells exhibit features of myelin-producing glia as well as astrocytes.