Epidemiology of salmonellosis in California, 1990-1999: Morbidity, mortality, and hospitalization costs
Epidemiology of salmonellosis in California, 1990-1999: Morbidity, mortality, and hospitalization costs
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DOI：
10.1093/aje/kwf155
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发表时间：
2003-01-01
影响因子：
5
通讯作者：
Vugia, DJ
中科院分区：
文献类型：
--
作者：
Trevejo, RT;Courtney, JG;Vugia, DJ
在美国，沙门氏菌是细菌性食源性疾病的常见原因。使用监测、住院和死亡数据描述了1990至1999年间加州非伤寒沙门氏菌病的流行病学和成本。沙门氏菌感染率的趋势和与延长住院时间相关的因素分别使用泊松模型和线性回归模型进行评估。有56,660例报告病例，11,102人住院，74人死于沙门氏菌。自1996年以来，报告病例和出院率均有所下降。在报告的病例中，婴儿发病率最高(每10(5)人年121例)，其次是1-4岁儿童(每10(5)人年40例)。老年人和幼儿的住院率最高。大多数死亡发生在65岁或以上的人中(59%)。在住院中，胃肠炎(61%)和败血症(23%)是最常见的沙门氏菌诊断。沙门氏菌肺炎患者年龄最大(中位年龄，55岁)，沙门氏菌脑膜炎患者最年轻(中位年龄，0.3岁)。这两种诊断的费用最高，接近每次住院3万美元(中位数)。有获得性免疫缺陷综合征诊断或多个沙门氏菌诊断与住院时间延长独立相关。沙门氏菌10年的住院费用估计为2亿美元。沙门氏菌病是一种代价高昂的疾病，对年轻人和老年人的影响不成比例。
Salmonella is a common cause of bacterial foodborne illness in the United States. The epidemiology and costs of nontyphoidal salmonellosis in California from 1990 through 1999 are described using surveillance, hospitalization, and death data. Trends in Salmonella rates and factors associated with prolonged hospitalization were evaluated using Poisson and linear regression models, respectively. There were 56,660 reported cases, 11,102 hospitalizations, and 74 deaths attributed to Salmonella. Reported case and hospital discharge rates have decreased since 1996. Among reported cases, infants had the highest rate (121 cases per 10(5) person-years), followed by children 1-4 years of age (40 cases per 10(5) person-years). The highest hospitalization rates were among the elderly and young children. Most deaths occurred among persons aged 65 or more years (59%). Among hospitalizations, gastroenteritis (61%) and septicemia (23%) were the most common Salmonella diagnoses. Salmonella pneumonia patients were the oldest (median age, 55 years) and Salmonella meningitis patients the youngest (median age, 0.3 years). These two diagnoses were the costliest, approaching $30,000 (median) per hospitalization. Having an acquired immunodeficiency syndrome diagnosis or multiple Salmonella diagnoses was independently associated with prolonged hospitalization. The estimated 10-year hospitalization costs for Salmonella were $200 million. Salmonellosis is a costly disease that disproportionately affects the young and elderly.