Blood pressure regulation in baroreceptor-denervated rats.
Blood pressure regulation in baroreceptor-denervated rats.
复制标题
压力感受器去神经大鼠的血压调节。
DOI：
10.1111/j.1440-1681.1997.tb01787.x
复制
发表时间：
1997
影响因子：
2.9
通讯作者：
KostJr,CK
中科院分区：
文献类型：
--
作者：
Sved,AF;Schreihofer,AM;KostJr,CK
1.动脉压力感受器去神经可引起急性高血压，但慢性去神经动物的平均动脉压与压力感受器正常动物的平均动脉压相近。2.尽管心肺压力感受器和肾代偿被认为可以调节去窦弓神经大鼠正常平均动脉压的恢复，但这种机制与已有的数据不一致。3.目前，慢性压力感受器失神经动物恢复和长期维持正常平均动脉压的过程尚不清楚。了解在动脉压力感受器反射缺失的情况下发生的动脉压调节，可能会为动脉压长期调节的机制提供重要的新见解。
1. Arterial baroreceptor denervation produces acute hypertension, but chronically denervated animals have an average arterial pressure that is similar to that of baroreceptor intact animals. 2. Although cardiopulmonary baroreceptors and renal compensations have been suggested to mediate the restoration of a normal average arterial pressure in sino-aortic denervated rats, such mechanisms are inconsistent with the available data. 3. At present the processes involved in the restoration and long-term maintenance of a normal average arterial pressure in chronic baroreceptor denervated animals are not known. An understanding of the regulation of arterial pressure that occurs in the absence of arterial baroreceptor reflexes may provide important new insights into the mechanisms underlying the long-term regulation of arterial pressure.