A new subtype classification of ischemic stroke based on treatment and etiologic mechanism
A new subtype classification of ischemic stroke based on treatment and etiologic mechanism
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DOI：
10.1159/000098059
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发表时间：
2007-01-01
影响因子：
2.4
通讯作者：
Heo, Ji Hoe
中科院分区：
文献类型：
--
作者：
Han, Sang Won;Kim, Seo Hyun;Heo, Ji Hoe
一种新的缺血性卒中亚型分类反映了最近的治疗策略以及卒中定义和机制的演变概念。在200例连续急性缺血性卒中患者中，评估了新分类系统的评估者间可靠性和亚型比例，并与急性卒中治疗（吐司）分类中的ORG 10172试验进行了比较。新分类中最常见的亚型是动脉粥样硬化血栓形成（n = 80，40%），其次是病因不明的卒中（n = 54，27%）、小动脉疾病（n = 33，16.5%）、心源性栓塞（n = 26，13%）和其他确定病因的卒中（n = 7，3.5%）。200例病例中，165例患者的3名评定者同意卒中亚型诊断，总体kappa值为优（kappa = 0.82）。新的脑梗死分类系统易于使用，具有较高的评分者间信度。版权所有（c）2007 S. Karger AG，巴塞尔。
A new subtype classification of ischemic stroke was developed to reflect recent therapeutic strategies as well as evolving concepts of stroke definitions and mechanisms. In 200 consecutive patients with acute ischemic stroke, the inter-rater reliability and proportion of subtypes of the new classification system were assessed and compared with those of the Trial of ORG 10172 in the Acute Stroke Treatment (TOAST) classification. The most frequent subtype of the new classification was atherothrombosis (n = 80, 40%), followed by stroke of undetermined etiology (n = 54, 27%), small artery disease (n = 33, 16.5%), cardioembolism (n = 26, 13%), and stroke of other determined etiology (n = 7, 3.5%). Three raters agreed to the stroke subtype diagnosis in 165 out of 200 cases and the overall kappa value was excellent (kappa = 0.82). The new classification system for brain infarction was easy to use and had high inter-rater reliability. Copyright (c) 2007 S. Karger AG, Basel.