Synthesis, Properties of Biodegradable Poly(Butylene Succinate-co-Butylene 2-Methylsuccinate) and Application for Sustainable Release
Synthesis, Properties of Biodegradable Poly(Butylene Succinate-co-Butylene 2-Methylsuccinate) and Application for Sustainable Release
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生物可降解聚(丁二酸丁二醇酯-2-甲基丁二酸丁二醇酯)的合成、性能及可持续释放应用
DOI：
10.3390/ma12091507
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发表时间：
2019-05-01
期刊：
影响因子：
3.4
通讯作者：
Guo, Baohua
中科院分区：
文献类型：
--
作者：
Han, Jiarui;Shi, Jiaxin;Guo, Baohua
以琥珀酸(SA)、2-甲基琥珀酸(MSA)和1，4-丁二醇(BDO)为原料，通过典型的两步酯化缩聚反应合成了一种新型的生物基可生物降解聚酯--聚(丁二酸丁二酸丁二醇酯-2-甲基琥珀酸丁二醇酯)(P(BS-BMS))。用核磁共振氢谱、核磁共振碳谱和凝胶渗透色谱对所得共聚物的化学结构和大分子质量进行了表征。用差示扫描量热法(DSC)研究了共混物的熔融温度和结晶度，发现随着MSA含量的增加，熔融温度和结晶度逐渐降低，而热重分析表明其热稳定性基本不变。此外，通过调节SA和MSA的比例可以控制P(BS-BMS)共聚物的生物降解率，这种生物降解性可以使P(BS-BMS)共聚物避免微塑料污染，从而可能在农业领域应用。采用预混膜乳化法(PME)制备的P(BS-BMS)共聚物作为农药载体，控制阿维菌素的释放，有效成分的分散性和利用率明显提高。阿维菌素呈现爆发式释放过程，随后阿维菌素长期持续释放，有望成为一种高效、环保的农药释放载体。
A novel biobased and biodegradable polyester, i.e., poly(butylene succinate-co-butylene 2-methylsuccinate) (P(BS-BMS)) was synthesized by succinic acid (SA), 2-methylsuccinic acid (MSA), and 1,4-butanediol (BDO) via a typically two-step esterification and polycondensation procedure. The chemical structure and macromolecular weight of obtained copolymers were characterized by 1H NMR, 13C NMR, and GPC. The melting temperature and degree of crystallinity were also studied by DSC, and it was found that the values were gradually decreased with increasing of MSA content, while the thermal stability remained almost unchanged which was tested by TGA. In addition, the biodegradation rate of the P(BS-BMS) copolymers could be controlled by adjusting the ratio of SA and MSA, and such biodegradability could make P(BS-BMS) copolymers avoid microplastic pollution which may be brought to the environment for applications in agricultural field. When we applied P(BS-BMS) copolymers as pesticide carriers which were prepared by premix membrane emulsification (PME) method for controlling Avermectin delivery, an improvement of dispersion and utilization of active ingredient was obviously witnessed. It showed a burst release process first followed by a sustained release of Avermectin for a long period, which had a great potential to be an effective and environmental friendly pesticide-release vehicle.