Vitamin D status in the United States, 2011-2014
Vitamin D status in the United States, 2011-2014
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DOI：
10.1093/ajcn/nqz037
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发表时间：
2019-07-01
影响因子：
7.1
通讯作者：
Potischman, Nancy
中科院分区：
文献类型：
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作者：
Herrick, Kirsten A.;Storandt, Renee J.;Potischman, Nancy
背景：维生素D对骨骼健康很重要；2014年，在医疗保险B部分支付中，它是第五大最常订购的实验室检查。目的：本研究的目的是描述2011-2014年美国人群中维生素D的状况以及2003 -2014年的趋势。方法：我们使用NHANES 2011-2014年的血清25-羟基维生素D数据（n = 16,180），并根据年龄、性别、种族和西班牙裔以及维生素D的膳食摄入量估算维生素D缺乏风险（< 30 nmol/L）或不足风险（30-49 nmol/L）的患病率。我们还提供了2003年至2014年的趋势。结果：2011-2014年，1岁儿童维生素D缺乏或不足的风险比例分别为5.0% （95% CI: 4.1%, 6.2%）和18.3% （95% CI: 16.2%, 20.6%）。在1-5岁的儿童中，有缺乏症风险的患病率最低（0.5%;95% CI: 0.3%, 1.1%），在20-39岁的成年人中达到峰值（7.6%;95% CI: 6.0%, 9.6%），在60岁的成年人中下降到2.9% (95% CI: 2.0%, 4.0%)；存在不足风险的普遍程度是相似的。非西班牙裔黑人（17.5%,95% CI: 15.2%, 20.0%）的缺乏风险患病率高于非西班牙裔亚裔（7.6%,95% CI: 5.9%, 9.9%）、非西班牙裔白人（2.1%,95% CI: 1.5%, 2.7%）和西班牙裔（5.9%,95% CI: 4.4%, 7.8%）人群；存在不足风险的普遍程度是相似的。膳食中维生素D摄入量较高或服用补充剂的人缺乏或不足维生素D的风险发生率较低。从2003年到2014年，维生素D缺乏的风险没有变化；不足的风险从21.0% （95% CI: 17.9%, 24.5%）下降到17.7% （95% CI: 16.0%, 19.7%）。结论：2003 - 2014年，美国维生素D缺乏症高危人群的患病率保持稳定；在风险不足的情况下下降。不同种族和西班牙裔的维生素D水平差异值得进一步调查。
Background: Vitamin D is important for bone health; in 2014 it was the fifth most commonly ordered laboratory test among Medicare Part B payments.Objectives: The aim of this study was to describe vitamin D status in the US population in 2011-2014 and trends from 2003 to 2014.Methods: We used serum 25-hydroxyvitamin D data from NHANES 2011-2014 (n = 16,180), and estimated the prevalence at risk of deficiency (< 30 nmol/L) or prevalence at risk of inadequacy (30-49 nmol/L) by age, sex, race and Hispanic origin, and dietary intake of vitamin D. We also present trends between 2003 and 2014.Results: In 2011-2014, the percentage aged= 1 y at risk of vitamin D deficiency or inadequacy was 5.0% (95% CI: 4.1%, 6.2%) and 18.3% (95% CI: 16.2%, 20.6%). The prevalence of at risk of deficiency was lowest among children aged 1-5 y (0.5%; 95% CI: 0.3%, 1.1%), peaked among adults aged 20-39 y (7.6%; 95% CI: 6.0%, 9.6%), and fell to 2.9% (95% CI: 2.0%, 4.0%) among adults aged >= 60 y; the prevalence of at risk of inadequacy was similar. The prevalence of at risk of deficiency was higher among non-Hispanic black (17.5%; 95% CI: 15.2%, 20.0%) than among non-Hispanic Asian (7.6%; 95% CI: 5.9%, 9.9%), non-Hispanic white (2.1%; 95% CI: 1.5%, 2.7%), and Hispanic (5.9%; 95% CI: 4.4%, 7.8%) persons; the prevalence of at risk of inadequacy was similar. Persons with higher vitamin D dietary intake or who used supplements had lower prevalences of at risk of deficiency or inadequacy. From 2003 to 2014 there was no change in the risk of vitamin D deficiency; the risk of inadequacy declined from 21.0% (95% CI: 17.9%, 24.5%) to 17.7% (95% CI: 16.0%, 19.7%).Conclusion: The prevalence of at risk of vitamin D deficiency in the United States remained stable from 2003 to 2014; at risk of inadequacy declined. Differences in vitamin D status by race and Hispanic origin warrant additional investigation.