Evaluation of Trabectome in Open-Angle Glaucoma
Evaluation of Trabectome in Open-Angle Glaucoma
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DOI：
10.1097/ijg.0b013e3182311b92
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发表时间：
2013-03-01
影响因子：
2
通讯作者：
Ichikawa, Kazuo
中科院分区：
文献类型：
--
作者：
Maeda, Masahiro;Watanabe, Mitsunori;Ichikawa, Kazuo
目的：为了评估结果的Trabectome，手术设备，消融一个弧的小梁网，在日本青光眼patients.Patients和方法：Trabectome手术进行了80眼的69名成年日本患者（年龄范围，14至89岁，50名男性和30名女性患者）或没有以前的手术或激光治疗。测量术前、术后Goldmann压平眼压、预防性用药、角膜内皮细胞密度和最佳矫正视力。结果：术前平均IOP为26.6 ± 8.1 mm Hg（范围：16 - 50 mm Hg），术后6个月平均IOP降至17.4 ± 3.4 mm Hg（范围：9 - 24 mm Hg）（降低28.7%）（N = 53）。术后6个月时，辅助药物从4.0 +/- 1.4降至2.3 +/- 1.2。100%的病例发生术中血液返流。没有出现威胁视力的并发症，如脉络膜积液、脉络膜出血或感染。13例（16.3%）在随访期间接受了再次手术，1例接受了白内障摘除术。没有显着的内皮细胞密度的变化recognized.Conclusion：Trabectome是一种有效和安全的替代传统的青光眼手术，通过6个月的预期约30%的IOP降低术后。
Purpose: To evaluate the outcomes of Trabectome, a surgical device that ablates an arc of trabecular meshwork, in Japanese glaucoma patients.Patients and Methods: Trabectome surgeries were performed on 80 eyes of 69 adult Japanese patients (age range, 14 to 89 y; 50 male and 30 female patients) with or without previous surgery or laser treatment. Goldmann applanation intraocular pressure (IOP), adjunctive medications, corneal endothelial cell density, and best corrected visual acuity were measured before and after surgery. Intraoperative and postoperative adverse events were also tabulated.Results: Mean preoperative IOP of 26.6 +/- 8.1 mm Hg (range, 16 to 50 mm Hg) decreased to a mean postoperative IOP of 17.4 +/- 3.4 mm Hg (range, 9 to 24 mm Hg) (28.7% reduction) by 6 months after surgery (N = 53). Adjunctive medication decreased from 4.0 +/- 1.4 to 2.3 +/- 1.2 at 6 months after surgery. Intraoperative blood reflux occurred in 100% of cases. No vision-threatening complications such as choroidal effusion, choroidal hemorrhage, or infection occurred. Thirteen cases (16.3%) received surgical reintervention and 1 case received cataract extraction during follow-up. No significant endothelial cell density change was recognized.Conclusion: Trabectome is an effective and safe alternative to traditional glaucoma surgeries with the expectation of approximately a 30% decrease in IOP through 6 months postoperatively.