Microvascular pressure in venules of skeletal muscle during arterial pressure reduction.
Microvascular pressure in venules of skeletal muscle during arterial pressure reduction.
复制标题
动脉压降低期间骨骼肌小静脉中的微血管压力。
DOI：
10.1152/ajpheart.1986.250.5.h838
复制
发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Johnson,PC
中科院分区：
文献类型：
--
作者：
House,SD;Johnson,PC
It has been suggested from whole organ studies that the viscosity of blood in skeletal muscle venules varies inversely with flow over physiological flow ranges. If this is the case, the hydrostatic pressure gradient in venules should change less than flow as flow is altered. To test this hypothesis, pressure in venules of cat sartorius muscle was measured during stepwise arterial pressure reduction to 20 mmHg. Large vein pressure remained constant at about 5 mmHg. Average pressures in the large venules (40–185 microns) ranged from 13.6 to 10.0 mmHg. The difference between pressure in these venules and large vein pressure fell in proportion to the reduction in blood pressure and blood flow. Pressures in the smallest venules studied (25 microns) averaged 19.7 +/- 6.2 (SD) mmHg. The pressure difference between the smallest venules and the large vein fell less than the arteriovenous pressure difference or blood flow when arterial pressure was reduced. During reactive hyperemia the pressure gradient between the smallest venules and the large vein rose proportionately less than blood flow. The stability of pressure in the smallest venules is consistent with the hypothesis that blood viscosity varies inversely with flow rate.
