Severe enterovirus A71 associated hand, foot and mouth disease, Vietnam, 2018: preliminary report of an impending outbreak.
Severe enterovirus A71 associated hand, foot and mouth disease, Vietnam, 2018: preliminary report of an impending outbreak.
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DOI：
10.2807/1560-7917.es.2018.23.46.1800590
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发表时间：
2018-11
期刊：
影响因子：
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通讯作者：
Tan LV
中科院分区：
文献类型：
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作者：
Nhan LNT;Hong NTT;Nhu LNT;Nguyet LA;Ny NTH;Thanh TT;Han DDK;Van HMT;Thwaites CL;Hien TT;Qui PT;Quang PV;Minh NNQ;van Doorn HR;Khanh TH;Chau NVV;Thwaites G;Hung NT;Tan LV
自2018年1月以来，越南各地发生了超过5.3万例手足口病住院治疗和6例死亡，其中大多数病例发生在9月以后。在胡志明市的一家大型三级转诊医院，肠道病毒A71亚基因组C4占主导地位，而B5仅零星检测到。2011 - 2012年，C4病毒在易感幼儿中引发严重手足口病暴发，导致200人死亡，这引发了人们对即将发生的另一场严重暴发的担忧。
Since January 2018, over 53,000 hospitalisations and six deaths due to hand, foot and mouth disease (HFMD) have occurred across Vietnam with most cases from September onward. In a large tertiary referral hospital, Ho Chi Minh City, enterovirus A71 subgenogroup C4 was predominant, while B5 was only sporadically detected. The re-emergence of C4 after causing a severe HFMD outbreak with > 200 deaths in 2011–12 among susceptible young children raises concern of another impending severe outbreak.