Interfacial Synthesis Part I: Phase-Transfer Catalyzed Synthesis of Polyhydroxy Ether
Interfacial Synthesis Part I: Phase-Transfer Catalyzed Synthesis of Polyhydroxy Ether
复制标题
界面合成第一部分：相转移催化合成多羟基醚
DOI：
10.1080/00222338108056777
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
J. Mcgrath
中科院分区：
文献类型：
--
作者：
A. K. Banthia;D. Lunsford;D. Webster;J. Mcgrath
摘要本文介绍了一种简便、快速、有效的合成线型、中等分子量多羟基醚的方法。该方法基于“相转移催化”原理，在碱-二氧六环水溶液体系中，以季铵盐作为迁移双酚A离子的有效试剂，在~ 86 ℃的回流温度下，使季铵化双酚A离子对与环氧氯丙烷反应。以高反应性的形式加入到有机相中。与涉及相转移催化剂的几种其它方法相比，本方法似乎对季铵盐具有真正的催化作用。聚乙二醇（MW 300- 14，000）作为相转移催化剂的成功使用也是非常重要的，因为它们的低毒性和相对低的成本。本文还简要介绍了相转移催化剂在制备高分子的两相体系中的作用。
Abstract A convenient, rapid and efficient method for the synthesis of linear, moderate molecular weight polyhydroxy ethers has been developed. Based on the principle of “phase-transfer catalysis” the method involves the reaction of quaternized bis-phenate ion-pair with epichlorohydrin in aqueous alkali-dioxane system, at the reflux temperature of ∼ 86°C, using a quaternary ammonium salt as an effective reagent for the transportation of the bis-phenate-A ion. to the organic phase in a highly reactive form. In contrast to several other processes where phase-transfer catalysts are involved, the present procedure appears to be truly catalytic with respect to quaternary ammonium salt. The successful use of polyethylene glycols (MW 300-14,000) as phase-transfer catalysts is also of great importance due to their low toxicity and relatively low cost. The role of phase-transfer catalysts in biphasic systems for preparative macromolecular systhesis has also been briefly outlined.