Treatment Patterns and Blood Pressure Control With Initiation of Combination Versus Monotherapy Antihypertensive Regimens
Treatment Patterns and Blood Pressure Control With Initiation of Combination Versus Monotherapy Antihypertensive Regimens
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DOI：
10.1161/hypertensionaha.120.15462
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发表时间：
2021-01-01
期刊：
影响因子：
8.3
通讯作者：
Reynolds, Kristi
中科院分区：
文献类型：
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作者：
An, Jaejin;Luong, Tiffany;Reynolds, Kristi
许多高血压患者需要 2 种或更多类别的药物才能达到血压 (BP) 目标。我们比较了开始联合治疗与单一治疗的患者的抗高血压药物治疗模式和血压控制。我们确定了在 2008 年至 2014 年间加入美国综合医疗保健系统并开始接受抗高血压药物治疗的高血压成年人。从电子健康记录中提取了患者人口统计数据、临床特征、抗高血压药物和血压。达到 2017 年美国心脏病学会/美国心脏协会指南推荐血压的抗高血压药物治疗模式和多变量调整患病率 (PR)
Many patients with hypertension require 2 or more drug classes to achieve their blood pressure (BP) goal. We compared antihypertensive medication treatment patterns and BP control between patients who initiated combination therapy versus monotherapy. We identified adults with hypertension enrolled in a US integrated healthcare system who initiated antihypertensive medication between 2008 and 2014. Patient demographics, clinical characteristics, antihypertensive medication, and BP were extracted from electronic health records. Antihypertensive medication patterns and multivariable adjusted prevalence ratios (PRs) of achieving the 2017 American College of Cardiology/American Heart Association guideline-recommended BP