Assessing breast tumor margin by multispectral photoacoustic tomography
Assessing breast tumor margin by multispectral photoacoustic tomography
复制标题
DOI：
10.1364/boe.6.001273
复制
发表时间：
2015-04-01
影响因子：
3.4
通讯作者：
Cheng, Ji-Xin
中科院分区：
文献类型：
--
作者：
Li, Rui;Wang, Pu;Cheng, Ji-Xin
在保乳手术过程中对乳腺癌切缘的高速和高度敏感的术中评估存在着一个未得到满足的需求。在这里，我们展示了一种多光谱光声断层成像系统，用于评估乳腺肿瘤边缘，使用脂肪和血红蛋白作为对比。该系统提供类似于3 mm的组织深度和类似于125微米的轴向分辨率。结果与组织学结果一致。手术切缘评估具有很高的敏感性，为术中切缘评估开辟了一条令人信服的途径。(C)2015年美国光学学会
An unmet need exists in high-speed and highly-sensitive intraoperative assessment of breast cancer margin during conservation surgical procedures. Here, we demonstrate a multispectral photoacoustic tomography system for breast tumor margin assessment using fat and hemoglobin as contrasts. This system provides similar to 3 mm tissue depth and similar to 125 mu m axial resolution. The results agreed with the histological findings. A high sensitivity in margin assessment was accomplished, which opens a compelling way to intraoperative margin assessment. (C)2015 Optical Society of America