The elastic properties of trabecular and cortical bone tissues are similar: results from two microscopic measurement techniques
The elastic properties of trabecular and cortical bone tissues are similar: results from two microscopic measurement techniques
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DOI：
10.1016/s0021-9290(98)00177-8
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发表时间：
1999-04-01
影响因子：
2.4
通讯作者：
Pharr, GM
中科院分区：
文献类型：
--
作者：
Turner, CH;Rho, J;Pharr, GM
声学显微镜(30-60微米分辨率)和纳米压痕(1-5微米分辨率)是可以在微观结构水平上评估人类骨骼弹性性质的技术。本研究的目标是(1)测量和比较来自普通人类供体的骨小梁和皮质骨组织的杨氏模数，以及(2)比较用声学显微镜测量的骨组织的杨氏模数和用纳米压痕测量的骨组织的杨氏模数。皮质骨纵向的杨氏模数比横向的杨氏模数大约40%(p<；0.01)。松质骨组织的杨氏模数略高于皮质骨的横向杨氏模数，但显著低于皮质骨的纵向杨氏模数。这些发现在两种测量方法中都是一致的，并表明骨小梁组织的弹性在皮质骨组织的范围内。用纳米压痕计算杨氏模数时，假定材料是弹性各向同性的。目前的结果，即由纳米压痕测定的皮质骨的平均各向异性比(E-L/E-T)与声学显微镜测定的结果相似，表明这一假设并不限制纳米压痕作为测量各向异性骨的杨氏模量的技术。(C)1999爱思唯尔科学有限公司。保留所有权利。
Acoustic microscopy (30-60 mu m resolution) and nanoindentation (1-5 mu m resolution) are techniques that can be used to evaluate the elastic properties of human bone at a microstructural level. The goals of the current study were (1) to measure and compare the Young's moduli of trabecular and cortical bone tissues from a common human donor, and (2) to compare the Young's moduli of bone tissue measured using acoustic microscopy to those measured using nanoindentation. The Young's modulus of cortical bone in the longitudinal direction was about 40% greater than (p < 0.01) the Young's modulus in the transverse direction. The Young's modulus of trabecular bone tissue was slightly higher than the transverse Young's modulus of cortical bone, but substantially lower than the longitudinal Young's modulus of cortical bone. These findings were consistent for both measurement methods and suggest that elasticity of trabecular tissue is within the range of that of cortical bone tissue. The calculation of Young's modulus using nanoindentation assumes that the material is elastically isotropic. The current results, i.e., the average anisotropy ratio (E-L/E-T for cortical bone determined by nanoindentation was similar to that determined by the acoustic microscope, suggest that this assumption does not limit nanoindentation as a technique for measurement of Young's modulus in anisotropic bone. (C) 1999 Elsevier Science Ltd. All rights reserved.