Diffuse optical imaging and spectroscopy for cancer
Diffuse optical imaging and spectroscopy for cancer
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DOI：
10.1586/17434440.4.1.83
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发表时间：
2007-01
影响因子：
3.1
通讯作者：
R. Xu;S. Povoski
中科院分区：
文献类型：
--
作者：
R. Xu;S. Povoski
可见光和近红外光通过吸收和散射与生物组织相互作用。漫射光学成像和光谱学是基于组织光学特性的无创测量来重建组织生理参数的。该技术可用于区分恶性和良性组织的生理和分子特征，因为它们涉及癌症研究领域。主要优点是使用非电离辐射，实时连续数据采集，成本低，便携式。局限性包括低空间分辨率和有限的再现性。本文综述了目前扩散光学成像和光谱技术的最新进展及其在癌症研究中的应用。
Visible light and near infrared light interact with biological tissue by absorption and scattering. Diffuse optical imaging and spectroscopy reconstructs tissue physiologic parameters based on noninvasive measurement of tissue optical properties. This technology can be used to differentiate physiologic and molecular signatures of both malignant and benign tissues, as they relate to the area of cancer research. Major advantages are the use of non-ionizing radiation, real-time continuous data acquisition, low cost, and portability. Limitations include low spatial resolution and limited reproducibility. This paper reviews the currently available state-of-the-art technologies for diffuse optical imaging and spectroscopy and their applications in cancer research.