Risk factors for lower extremity amputation in patients with diabetic foot ulcers: A meta-analysis
Risk factors for lower extremity amputation in patients with diabetic foot ulcers: A meta-analysis
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DOI：
10.1371/journal.pone.0239236
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发表时间：
2020-09-16
期刊：
影响因子：
3.7
通讯作者：
Sun, Hu
中科院分区：
文献类型：
--
作者：
Lin, Chunmei;Liu, Jinhao;Sun, Hu
每年有相当数量的糖尿病足溃疡（diabetic foot ulcer，DFU）患者需要截肢，这不仅影响了患者的生活质量，增加了社会负担，而且缩短了患者的预期寿命。考虑到这些负面影响，重要的是要探讨影响DFU患者截肢的相关危险因素。方法全面检索PubMed、SCIE和Embase数据库中2019年10月31日前发表的前瞻性或回顾性研究。包括所有英语语言研究涉及DFU患者，RevMan 5.3软件被用来分析data.ResultsThis荟萃分析包括21项研究，涉及6505名参与者，包括2006年患者需要下肢截肢。以下变量与截肢风险增加相关：男性（比值比（OR）= 1.30，95%置信区间（CI）= 1.16与1.46相似，P
PurposeA considerable number of diabetic foot ulcer (DFU) patients require amputation every year, which worsens their quality of life, aggravates the social burden, and shortens their life expectancy. Considering these negative effects, it is important to explore the relative risk factors affecting amputation in DFU patients. MethodsThe PubMed, SCIE and Embase databases were comprehensively searched for prospective or retrospective studies published before October 31, 2019. All English language studies involving DFU patients were included, and RevMan 5.3 software was used to analyse the data.ResultsThis meta-analysis includes 21 studies involving 6505 participants, including 2006 patients who required a lower limb amputation. The following variables were associated with an increased risk of amputation: male sex (odds ratios (OR) = 1.30, 95% confidence interval (CI) = 1.16 similar to 1.46, P