Spontaneous fluctuations in neural responses to heartbeats predict visual detection
Spontaneous fluctuations in neural responses to heartbeats predict visual detection
复制标题
DOI：
10.1038/nn.3671
复制
发表时间：
2014-04-01
影响因子：
25
通讯作者：
Tallon-Baudry, Catherine
中科院分区：
文献类型：
--
作者：
Park, Hyeong-Dong;Correia, Stephanie;Tallon-Baudry, Catherine
持续神经活动的自发波动实质上影响感觉和认知表现。由于身体信号不断地传递到新皮层，因此对身体信号的神经反应可能会影响正在进行的活动。在这里，使用脑磁图，我们表明，在人类中，神经事件锁定到刺激开始之前的心跳预测检测到一个微弱的视觉光栅在右后下顶叶小叶和腹侧前扣带皮层，两个区域，有多个功能相关，属于同一个休息状态网络。无论是测量的身体参数的波动，也没有整体皮质兴奋性可以解释这一发现。因此，锁定在心跳上的神经事件塑造了视觉意识体验，这可能是因为它们有助于形成有机体的神经地图，而神经地图可能是主观性的基础。除了有意识的视觉，我们的研究结果表明，神经事件锁定到一个基本的生理输入，如心跳的基础行为相关的差异激活多功能皮层区域。
Spontaneous fluctuations of ongoing neural activity substantially affect sensory and cognitive performance. Because bodily signals are constantly relayed up to the neocortex, neural responses to bodily signals are likely to shape ongoing activity. Here, using magnetoencephalography, we show that in humans, neural events locked to heartbeats before stimulus onset predict the detection of a faint visual grating in the posterior right inferior parietal lobule and the ventral anterior cingulate cortex, two regions that have multiple functional correlates and that belong to the same resting-state network. Neither fluctuations in measured bodily parameters nor overall cortical excitability could account for this finding. Neural events locked to heartbeats therefore shape visual conscious experience, potentially by contributing to the neural maps of the organism that might underlie subjectivity. Beyond conscious vision, our results show that neural events locked to a basic physiological input such as heartbeats underlie behaviorally relevant differential activation in multifunctional cortical areas.