3D CT modeling of hepatic vessel architecture and volume calculation in living donated liver transplantation
3D CT modeling of hepatic vessel architecture and volume calculation in living donated liver transplantation
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DOI：
10.1007/s00330-003-2161-8
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发表时间：
2004-02-01
影响因子：
5.9
通讯作者：
Galanski, M
中科院分区：
文献类型：
--
作者：
Frericks, BB;Caldarone, FC;Galanski, M
本研究的目的是评估一种软件工具，用于活体捐献肝移植（LDLT）中潜在供体的无创术前体积评估。对56例潜在供体行双相螺旋CT检查。使用非商业软件工具对数据集进行后处理，用于肝段的分割、体积分析和可视化。肝边缘的半自动定义允许对实质进行分割。使用具有自动确定阈值的区域生长算法来描绘肝血管。根据门静脉分支自动计算肝段的体积和形状。对27例移植病例进行三维可视化，并与常规容积法及术中表现进行统计学比较。图像处理很容易在23分钟内完成。在56例潜在供体中，27例因肝实质或血管结构不合适而被排除在LDLT之外。2例受者因临床条件差未能移植。在27例移植病例中，术前可见血管被证实，只有1例未被发现的肝副静脉被发现。计算的移植物体积为右叶1110+/-180 ml，左叶820 ml， II+III节段270+/-30 ml。计算体积与术中测量的移植物体积相关性显著。自动容积法与常规容积法无显著差异。评估了一种新的图像处理技术，该技术允许半自动体积计算和不同肝段的3D可视化。
The aim of this study was to evaluate a software tool for non-invasive preoperative volumetric assessment of potential donors in living donated liver transplantation (LDLT). Biphasic helical CT was performed in 56 potential donors. Data sets were post-processed using a non-commercial software tool for segmentation, volumetric analysis and visualisation of liver segments. Semi-automatic definition of liver margins allowed the segmentation of parenchyma. Hepatic vessels were delineated using a region-growing algorithm with automatically determined thresholds. Volumes and shapes of liver segments were calculated automatically based on individual portal-venous branches. Results were visualised three-dimensionally and statistically compared with conventional volumetry and the intraoperative findings in 27 transplanted cases. Image processing was easy to perform within 23 min. Of the 56 potential donors, 27 were excluded from LDLT because of inappropriate liver parenchyma or vascular architecture. Two recipients were not transplanted due to poor clinical conditions. In the 27 transplanted cases, preoperatively visualised vessels were confirmed, and only one undetected accessory hepatic vein was revealed. Calculated graft volumes were 1110+/-180 ml for right lobes, 820 ml for the left lobe and 270+/-30 ml for segments II+III. The calculated volumes and intraoperatively measured graft volumes correlated significantly. No significant differences between the presented automatic volumetry and the conventional volumetry were observed. A novel image processing technique was evaluated which allows a semi-automatic volume calculation and 3D visualisation of the different liver segments.