Early-life determinants of overweight and obesity: a review of systematic reviews
Early-life determinants of overweight and obesity: a review of systematic reviews
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DOI：
10.1111/j.1467-789x.2010.00735.x
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发表时间：
2010-10-01
期刊：
影响因子：
8.9
通讯作者：
Brug, J.
中科院分区：
文献类型：
--
作者：
Monasta, L.;Batty, G. D.;Brug, J.
这篇文章的目的是回顾早期（从怀孕到5岁）肥胖决定因素的证据。本研究的设计是对已发表的系统性综述进行综述。数据来源包括Medline、Embase、Web of Science、科克伦图书馆、CINAHL、PsycInfo。从包含12021篇独立出版物的数据库中识别出22篇符合条件的综述。使用多个系统评价评分评估选定评价的质量。使用审查后发表的文章来确认结果。没有评论被归类为高质量，11个为中等，11个为低质量。与后来超重和肥胖相关的因素：母亲糖尿病，母亲吸烟，婴儿快速生长，没有母乳喂养或母乳喂养时间短，婴儿肥胖，睡眠时间短，每日体力活动< 30分钟，饮用含糖饮料。其他因素也被确定为潜在相关因素，但其影响程度难以估计。母亲吸烟、母乳喂养、婴儿体型和生长、睡眠时间短和看电视等都得到了质量更高的评论的支持。很难在可能的决定因素和肥胖之间建立因果关系，以及每个决定因素的相对重要性。未来的研究应侧重于早期干预，以确认保护和风险因素的作用，并解决肥胖对今世后代的高负担问题。
P>The aim of this paper was to review the evidence for early-life (from conception to 5 years of age) determinants of obesity. The design is review of published systematic reviews. Data sources included Medline, Embase, Web of Science, Cochrane Library, CINAHL, PsycINFO. Identification of 22 eligible reviews from a database of 12 021 independent publications. Quality of selected reviews assessed using the Assessment of Multiple Systematic Reviews score. Articles published after the reviews were used to confirm results. No review was classified as high quality, 11 as moderate and 11 as low. Factors associated with later overweight and obesity: maternal diabetes, maternal smoking, rapid infant growth, no or short breastfeeding, obesity in infancy, short sleep duration, < 30 min of daily physical activity, consumption of sugar-sweetened beverages. Other factors were identified as potentially relevant, although the size of their effect is difficult to estimate. Maternal smoking, breastfeeding, infant size and growth, short sleep duration and television viewing are supported by better-quality reviews. It is difficult to establish a causal association between possible determinants and obesity, and the relative importance of each determinant. Future research should focus on early-life interventions to confirm the role of protective and risk factors and to tackle the high burden obesity represents for present and future generations.