Visible-Light-Promoted Transition-Metal-Free Phosphinylation of Heteroaryl Halides in the Presence of Potassium tert-Butoxide
Visible-Light-Promoted Transition-Metal-Free Phosphinylation of Heteroaryl Halides in the Presence of Potassium tert-Butoxide
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叔丁醇钾存在下可见光促进杂芳基卤化物的无过渡金属膦酰化
DOI：
10.1021/acs.orglett.8b03265
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发表时间：
2018
期刊：
影响因子：
5.2
通讯作者：
Che Chi-Ming
中科院分区：
文献类型：
--
作者：
Yuan Jia;To Wai-Pong;Zhang Zi-Yang;Yue Chang-Duo;Meng Sixuan;Chen Jian;Liu Yungen;Yu Guang-Ao;Che Chi-Ming
公开了一种在不存在过渡金属和光氧化还原催化剂的情况下的新型可见光促进的C-P键形成反应。通过使用容易获得和廉价的杂芳基氯化物/溴化物作为底物，以中等至良好的产率获得了各种杂芳基氧化膦。这种策略提供了一种简单而有效的杂芳基氧化膦的路线。
A novel visible-light-promoted C–P bond formation reaction in the absence of both transition metal and photoredox catalysts is disclosed. By employing easily available and inexpensive heteroaryl chlorides/bromides as substrates, a variety of heteroaryl phosphine oxides were obtained in moderate to good yields. This strategy provides a simple and efficient route to heteroaryl phosphine oxides.