Noise and poise: Enhancement of postural complexity in the elderly with a stochastic-resonance-based therapy
Noise and poise: Enhancement of postural complexity in the elderly with a stochastic-resonance-based therapy
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DOI：
10.1209/0295-5075/77/68008
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发表时间：
2007-01-01
期刊：
影响因子：
1.8
通讯作者：
Peng, C. K.
中科院分区：
文献类型：
--
作者：
Costa, M.;Priplata, A. A.;Peng, C. K.
病理状态与动力学复杂性的丧失有关。因此，增加生理复杂性的治疗干预可能会改善健康状况。使用多尺度熵分析，我们表明健康年轻人和健康老年人受试者的姿势摇摆动力学比有福尔斯跌倒史的老年人受试者更复杂。对足部应用感觉下噪声已被证明可以改善老年人的姿势稳定性。我们接下来表明，这种疗法显着增加了多尺度复杂性的摇摆波动在健康的老年人。生物变异性的动态复杂性的变化的量化可能是一种新的方法来评估风险和预测临床干预措施，包括基于噪声的治疗的疗效的基础。
Pathologic states are associated with a loss of dynamical complexity. Therefore, therapeutic interventions that increase physiologic complexity may enhance health status. Using multiscale entropy analysis, we show that the postural sway dynamics of healthy young and healthy elderly subjects are more complex than that of elderly subjects with a history of falls. Application of subsensory noise to the feet has been demonstrated to improve postural stability in the elderly. We next show that this therapy significantly increases the multiscale complexity of sway fluctuations in healthy elderly subjects. Quantification of changes in dynamical complexity of biologic variability may be the basis of a new approach to assessing risk and to predicting the efficacy of clinical interventions, including noise-based therapies.