3 MODES OF TRANSMISSION OF ROSS RIVER VIRUS BY AEDES-VIGILAX (SKUSE)

3 MODES OF TRANSMISSION OF ROSS RIVER VIRUS BY AEDES-VIGILAX (SKUSE)
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DOI:
10.1038/icb.1982.37
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发表时间:
1982-01-01
期刊:
AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE
影响因子:
--
通讯作者:
KAY, BH
KAY, BH
中科院分区:
其他
文献类型:
--
作者:
KAY, BH

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约15%的盐沼蚊A.(Ochlerotatus)vigilax(Skuse)将罗斯河病毒的T48株从病毒血症供体机械地传播给未感染的受体乳鼠。来自布里斯班[澳大利亚]附近的受试人群对感染中度敏感(感染剂量中位数= 104.5 ± 0.001)。0.1乳鼠LD 50/蚊)。病毒在蚊子体内的快速增殖使其在摄入后4天开始传播,最大传播率为50-57%,发生在10天后。从A.对于vigilax卵巢和由父母感染的雌性饲养的后代,初步数据表明经卵巢传播是该病毒的潜在生存方式。
Some 15% of the saltmarsh mosquito, A. (Ochlerotatus) vigilax (Skuse) mechanically transmitted the T48 strain of Ross River virus from viremic donors to uninfected recipient suckling mice. The population tested from near Brisbane [Australia] was moderately susceptible to infection (median infective dose = 104.5.+-.0.1 suckling mouse LD50/mosquito) when fed virus diluted in blood on a cotton pledget. Rapid proliferation of the virus in the mosquito allowed transmission from 4 days after ingestion with maximum transmission of 50-57% occurring from 10 days. From assay of A. vigilax ovaries and of progeny reared from parentally-infected females, preliminary data suggest transovarial transmission as a potential survival method for this virus.