Structure of a new pseudaminic acid-containing capsular polysaccharide of Acinetobacter baumannii LUH5550 having the KL42 capsule biosynthesis locus
Structure of a new pseudaminic acid-containing capsular polysaccharide of Acinetobacter baumannii LUH5550 having the KL42 capsule biosynthesis locus
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DOI：
10.1016/j.carres.2015.02.006
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发表时间：
2015-04-30
影响因子：
3.1
通讯作者：
Knirel, Yuriy A.
中科院分区：
文献类型：
--
作者：
Senchenkova, Sof'ya N.;Popova, Anastasiya V.;Knirel, Yuriy A.
用1D和2D H-1和C-13 NMR研究了鲍曼不动杆菌LUH 5550荚膜多糖的结构。其中Pse 5Ac 7 RHb表示5-乙酰氨基-3，5，7，9-四脱氧-7-[（R）-3-羟基丁酰基氨基]-L-甘油基-L-甘露-壬-2-酮糖酸。命名为KL 42的荚膜生物合成基因座中的基因与所建立的结构一致。(C)2015爱思唯尔有限公司版权所有。
The capsular polysaccharide from Acinetobacter baumannii LUH5550 was studied by 1D and 2D H-1 and C-13 NMR spectroscopy. The following structure of the branched trisaccharide repeating unit was established:[GRAPHICS]where Pse5Ac7RHb indicates 5-acetamido-3,5,7,9-tetradeoxy-7-[(R)-3-hydroxybutanoylamino]-L-glycero- L-manno-non-2-ulosonic acid. The genes in the capsule biosynthesis locus designated KL42 are consistent with the structure established. (C) 2015 Elsevier Ltd. All rights reserved.