HEPATIC CIRRHOSIS - CLINICOPATHOLOGICAL REVIEW OF 520 CASES

HEPATIC CIRRHOSIS - CLINICOPATHOLOGICAL REVIEW OF 520 CASES
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DOI:
10.1136/jcp.26.12.936
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发表时间:
1973-01-01
影响因子:
3.4
通讯作者:
SCOTT, AR
SCOTT, AR
中科院分区:
医学3区
文献类型:
--
作者:
MACSWEEN, RN;SCOTT, AR

文献摘要

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本文报告了1900 ~ 1969年在格拉斯哥西部医院进行尸检的520例肝硬化患者的临床病理学回顾。自20世纪40年代以来,肝硬化的发病率总体上有所增加,这主要是由于女性发病率的上升。从苏格兰注册总署的年度报告中提取的数据证实了1940- 1971年期间的类似趋势,男女的平均死亡年龄都有所上升。病因学上,酒精性肝硬化占18.5%,黄疸后肝硬化占10.4%,隐源性肝硬化占61.9%,血色病占7.5%。原发性肝脏恶性肿瘤占12.3%。死亡原因和肝硬化的形态学模式进行了审查。
A clinico-pathological review of 520 patients with hepatic cirrhosis coming to necropsy at the Western Infirmary, Glasgow over the period 1900-69 is reported. There has been an overall increase in incidence of cirrhosis since the 1940s, and this has been largely due to a rise in female incidence. A similar trend in the period 1940-71 has been confirmed at a national level in data abstracted from the Annual Reports of the Registrar General for Scotland.The mean age at death has risen for both sexes. Aetiologically, the cirrhosis was alcoholic in 18·5%, posticteric in 10·4%, cryptogenic in 61·9%, and haemochromatosis was diagnosed in 7·5%. Primary malignant tumours of liver supervened in 12·3%. The causes of death and the morphological patterns of the cirrhosis are reviewed.