The Great East Japan Earthquake Disaster and cardiovascular diseases
The Great East Japan Earthquake Disaster and cardiovascular diseases
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DOI：
10.1093/eurheartj/ehs288
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发表时间：
2012-11-01
影响因子：
39.3
通讯作者：
Shimokawa, Hiroaki
中科院分区：
文献类型：
--
作者：
Aoki, Tatsuo;Fukumoto, Yoshihiro;Shimokawa, Hiroaki
虽然以前的研究报告了大地震后个体心血管疾病（CVD）的短期增加，但大地震后所有类型的CVD的中期发生率尚不清楚。我们在东日本大地震（2011年3月11日）的经验中探讨了这一重要问题，通过比较灾区中心的宫城县2008年11（n 124 152）期间医生的救护记录，回顾性地研究了地震对心血管疾病和肺炎发生的影响。与地震前3年相比，地震后心血管疾病（包括心力衰竭（HF）、急性冠状动脉综合征（ACS）、中风、心肺骤停（CPA）和肺炎）的每周发生率均显著增加。ACS和CPA的发生率显示出快速增加，然后急剧下降，而HF和肺炎的发生率显示出超过6周的持续增加，而卒中和CPA的发生率在最大余震（2011年4月7日）后显示出第二个高峰。此外，地震后24小时内CPA的发病率增加，随后是其他疾病，这些增加与年龄、性别和居住地无关这些结果表明，在地震后的不同时间过程中，所有类型的心血管疾病和肺炎的发生率都有所增加，包括首次观察到HF的显著和长期增加，强调了大地震后对所有类型的CVD进行强化医疗管理的重要性。
While previous studies reported a short-term increase in individual cardiovascular disease (CVD) after great earthquakes, mid-term occurrences of all types of CVDs after great earthquakes are unknown. We addressed this important issue in our experience with the Great East Japan Earthquake (11 March 2011).We retrospectively examined the impact of the Earthquake on the occurrences of CVDs and pneumonia by comparing the ambulance records made by doctors in our Miyagi Prefecture, the centre of the disaster area, during the periods of 200811 (n 124 152). The weekly occurrences of CVDs, including heart failure (HF), acute coronary syndrome (ACS), stroke, cardiopulmonary arrest (CPA), and pneumonia were all significantly increased after the Earthquake compared with the previous 3 years. The occurrences of ACS and CPA showed the rapid increase followed by a sharp decline, whereas those of HF and pneumonia showed a prolonged increase for more than 6 weeks and those of stroke and CPA showed a second peak after the largest aftershock (7 April 2011). Furthermore, the occurrence of CPA was increased in the first 24 h after the Earthquake, followed by other diseases later on. These increases were independent of age, sex, or residence area (seacoast vs. inland).These results indicate that the occurrences of all types of CVDs and pneumonia were increased in somewhat different time courses after the Earthquake, including the first observation of the marked and prolonged increase in HF, emphasizing the importance of intensive medical management of all types of CVDs after great earthquakes.