Long-term outcomes of pediatric moyamoya disease monitored to adulthood
Long-term outcomes of pediatric moyamoya disease monitored to adulthood
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DOI：
10.1016/s0887-8994(97)00209-9
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发表时间：
1998-04-01
影响因子：
3.8
通讯作者：
Fukuyama, Y
中科院分区：
文献类型：
--
作者：
Imaizumi, T;Hayashi, K;Fukuyama, Y
25例儿童烟雾病患者（18例为短暂性脑缺血发作型，7例为非短暂性脑缺血发作型）的长期预后监测至成年期（年龄大于20岁），在剩余临床症状、智力发展和日常生活活动方面进行评估。手术治疗10例，脑硬动脉合并症9例，颞浅动脉与大脑中动脉吻合合并脑肌合并症1例。只有7例TIA型患者（3例手术治疗，4例药物治疗）表现出良好的日常生活活动，无TIA或头痛，智商正常，2例TIA型患者和3例非TIA型患者预后较差。其中3例预后不良的患者有肾动脉狭窄，9例手术有效。由于儿童烟雾病患者的长期预后通常较差，手术治疗被认为是预防临床症状进展的有效方法。(C) 1998年Elsevier Science Inc。版权所有。
The long-term outcomes of 25 patients with childhood moyamoya disease (18 with the transient ischemic attack [TIA] type and seven with the non-TIA type), who were monitored to adulthood (older than 20 years of age), were evaluated in terms of residual clinical symptoms, intellectual development, and activities of daily living. Surgical treatment was performed in ten patients, encephaloduroarteriosynangiosis in nine, and superficial temporal artery to middle cerebral artery anastomosis plus encephalomyosynangiosis in one. only seven with the TIA type (three surgically and four medically treated) demonstrated good activities of daily living without TIA or headache and normal IQ, Two patients with the TIA type and three with the non-TIA type demonstrated poor outcomes. Three of these patients with poor outcomes had renal artery stenosis, Surgery was effective in nine. Since the longterm outcomes of patients with childhood moyamoya disease are generally poor, surgical treatment is believed to be an effective procedure for preventing the progression of clinical symptoms. (C) 1998 by Elsevier Science Inc. All rights reserved.