Daily associations with cannabis use and sleep quality in anxious cannabis users.
Daily associations with cannabis use and sleep quality in anxious cannabis users.
复制标题
焦虑的大麻使用者的日常与大麻使用和睡眠质量的关联。
DOI：
10.1080/15402002.2023.2217969
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发表时间：
2024
影响因子：
3.1
通讯作者：
Hitchcock,LH
中科院分区：
文献类型：
--
作者：
Bidwell,LC;Sznitman,SR;Martin-Willett,R;Hitchcock,LH
大麻越来越多地用于自我治疗焦虑和相关的睡眠问题，没有明确的证据支持或反驳其抗焦虑或助眠作用。此外，不同形式的大麻和主要大麻素∆9-四氢大麻酚（THC）和大麻二酚（CBD）具有不同的药理作用。方法收集使用大麻治疗轻度至中度焦虑的个体（n= 347，男性36%，女性64%，平均年龄= 33岁）30天的睡眠质量和大麻使用情况的每日数据。参与者自我报告了在观察期间使用的大麻的形式（花或可食用）和THC与CBD的比例。结果在某一天使用大麻的人在第二天晚上的睡眠质量也更好。适度分析表明，对于基线情感症状较高的应答者来说，使用大麻后感觉睡眠更好。此外，使用CBD浓度高的大麻食品的受访者报告了最高的睡眠质量。结论：在有情感症状的个体中，自然使用大麻与更好的睡眠质量有关，特别是对于那些使用食用和CBD主导产品的人。
IntroductionCannabis is increasingly used to self-treat anxiety and related sleep problems, without clear evidence of either supporting or refuting its anxiolytic or sleep aid effects. In addition, different forms of cannabis and primary cannabinoids ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) have differing pharmacological effects.MethodsThirty days of daily data on sleep quality and cannabis use were collected in individuals who use cannabis for mild-to-moderate anxiety (n= 347; 36% male, 64% female; mean age = 33 years). Participants self-reported both the form (flower or edible) and the ratio of THC to CBD in the cannabis used during the observation period.ResultsIndividuals who reported cannabis use on a particular day also reported better sleep quality the following night. Moderation analyses showed that better perceived sleep after cannabis use days was stronger for respondents with higher baseline affective symptoms. Further, respondents who used cannabis edibles with high CBD concentration reported the highest perceived quality of sleep.ConclusionsAmong individuals with affective symptoms, naturalistic use of cannabis was associated with better sleep quality, particularly for those using edible and CBD dominant products.