Ligand-selective determinants in gonadotropin receptors
Ligand-selective determinants in gonadotropin receptors
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DOI：
10.1016/j.mce.2006.01.019
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发表时间：
2007-01-02
影响因子：
4.1
通讯作者：
Bogerd, J.
中科院分区：
文献类型：
--
作者：
Bogerd, J.
在哺乳动物中，促性腺激素与其同源受体之间的相互作用是高度特异性的;在正常生理条件下未观察到意外的交叉反应性。本文总结了旨在阐明配体选择性的分子基础的比较结构-功能研究。(c)2006爱思唯尔爱尔兰有限公司保留所有权利。
In mammals, the interactions between gonadotropins and their cognate receptors are highly specific; unintended cross-reactivity under normal physiological conditions has not been observed. This paper summarizes the comparative structure-function studies that aim at elucidating the molecular basis of the ligand selectivity. (c) 2006 Elsevier Ireland Ltd. All rights reserved.