ULTRASONIC EVALUATION OF EARLY CAROTID ATHEROSCLEROSIS
ULTRASONIC EVALUATION OF EARLY CAROTID ATHEROSCLEROSIS
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DOI：
10.1161/01.str.21.11.1567
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发表时间：
1990-11-01
期刊：
影响因子：
8.3
通讯作者：
KAMADA, T
中科院分区：
文献类型：
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作者：
HANDA, N;MATSUMOTO, M;KAMADA, T
我们调查了232名连续的日本患者的颈动脉粥样硬化的患病率，包括轻度早期病变，及其与颈部杂音和各种危险因素（年龄、男性、高血压、高脂血症、糖尿病、肥胖和吸烟）的关系。进行高分辨率实时B型超声检查以确定动脉粥样硬化的程度，并使用评分系统对其进行量化。所有232名患者、100名有症状患者和132名无症状患者的颈动脉粥样硬化患病率分别为49%、59%和41%。虽然在30例颈部杂音患者中经常检测到颈动脉病变（87%），但在88例颈动脉粥样硬化患者中仅30%观察到杂音。这些患者颈动脉粥样硬化的独立危险因素是年龄、男性和高脂血症;糖尿病是颈动脉粥样硬化的可能危险因素。我们的研究没有显示高血压和颈动脉粥样硬化之间的密切联系，这可能是由于我们的患者中高血压的高患病率造成的。我们的研究结果表明，日本人颈动脉粥样硬化的患病率不断增加，但这一点应在以人群为基础的研究中得到证实。我们的研究证实了高分辨率B型超声检查对早期颈动脉粥样硬化评估的临床价值。
We investigated the prevalence of carotid atherosclerosis, including mild early lesions, and its association with cervical bruits and various risk factors (age, male sex, hypertension, hyperlipidemia, diabetes mellitus, obesity, and cigarette smoking) in 232 consecutive Japanese patients. High-resolution real-time B-mode ultrasonography was performed to determine the extent of atherosclerosis, and it was quantified by using a scoring system. The prevalence of carotid atherosclerosis was 49%, 59%, and 41% in all 232 patients, the 100 symptomatic patients, and the 132 asymptomatic patients, respectively. Although carotid lesions were detected frequently (87%) in the 30 patients with cervical bruits, bruits were noted in only 30% of the 88 examined patients with carotid atherosclerosis. Independent risk factors for carotid atherosclerosis in these patients were found to be age, male sex, and hyperlipidemia; diabetes mellitus was a possible risk factor for carotid atherosclerosis. Our study did not show a close association between hypertension and carotid atherosclerosis, and this might be caused by the high prevalence of hypertension in our patients. Our findings suggest an increasing prevalence of carotid atherosclerosis in the Japanese, though this should be confirmed in a population-based study. Our study demonstrates the clinical usefulness of high-resolution B-mode ultrasonography for the evaluation of early carotid atherosclerosis.