Impact of cognitive frailty on daily activities in older persons
Impact of cognitive frailty on daily activities in older persons
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DOI：
10.1007/s12603-016-0685-2
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发表时间：
2016-07-01
影响因子：
5.8
通讯作者：
Suzuki, T.
中科院分区：
文献类型：
--
作者：
Shimada, H.;Makizako, H.;Suzuki, T.
确定社区老年人身体和/或认知虚弱与工具性日常生活活动（IADL）功能之间的关系。横断面观察研究。数据摘自2011-2013年国家老年医学和老年学中心-老年Syndrome研究（NCGG-SGS）数据库。共有8，864名年龄在65岁以上的老年人参加了NCGG-SGS。我们将身体虚弱的特征描述为以下五个领域中的三个或更多个领域的限制：步行速度慢、肌肉无力、疲惫、活动量少和体重减轻。为了筛查认知障碍，我们使用了国家老年医学和老年学中心功能评估工具（NCGG-FAT），其中包括单词列表记忆、注意力和执行功能（连线测试的平板电脑版本，A和B部分）以及处理速度（数字符号替代测试的平板电脑版本）。两个或两个以上的认知功能障碍，年龄调整后的评分低于参考阈值至少1.5个标准差，被定性为认知功能障碍。每位参与者报告了他们的IADL状态（使用公共交通、购物、财务管理和家务管理）和几个潜在的混杂因素，如人口统计学特征。身体虚弱、认知障碍和认知虚弱（即虚弱和认知障碍并存）的总体患病率分别为7.2%、5.2%和1.2%。我们发现IADL限制和身体虚弱之间存在显着关系（比值比（OR）1.24，95%置信区间（95% CI）1.01至1.52），认知功能障碍（OR 1.71，95% CI 1.39 - 2.11），和认知功能障碍（OR 2.63，95%CI 1.74 - 3.97）。使用NCGG-SGS虚弱标准，我们发现身体虚弱的参与者多于认知虚弱的参与者。认知功能不全的个体发生IADL限制的风险最高。未来的调查是必要的，以确定这一人群是否在残疾或死亡率的发病率增加的风险。
To identify the relationships between physical and/or cognitive frailty and instrumental activities of daily living (IADL) functioning in community living older persons.Cross sectional observation study.Data extracted from the 2011-2013 of the National Center for Geriatrics and Gerontology-Study of Geriatric Syndromes (NCGG-SGS) database.A total of 8,864 older adults aged aeyen 65 years who were enrolled in the NCGG-SGS.We characterized physical frailty as limitations in three or more of the following five domains: slow walking speed, muscle weakness, exhaustion, low activity and weight loss. To screen for cognitive impairment, we used the National Center for Geriatrics and Gerontology-Functional Assessment Tool (NCGG-FAT) which included tests of word list memory, attention and executive function (tablet version of the Trail Making Test, part A and B), and processing speed (tablet version of the Digit Symbol Substitution Test). Two or more cognitive impairments indicated by an ageadjusted score of at least 1.5 standard deviations below the reference threshold was characterized as cognitive impairment. Each participant reported on their IADL status (use of public transportation, shopping, management of finances, and housekeeping) and several potential confounders such as demographic characteristics.The overall prevalence of physical frailty, cognitive impairment, and cognitive frailty, i.e. co-occurrence of frailty and cognitive impairment, was 7.2%, 5.2%, and 1.2%, respectively. We found significant relationships between IADL limitations and physical frailty (Odds Ratio (OR) 1.24, 95% confidence interval (95% CI) 1.01 to 1.52), cognitive impairment (OR 1.71, 95% CI 1.39 to 2.11), and cognitive frailty (OR 2.63, 95% CI 1.74 to 3.97).Using the NCGG-SGS frailty criteria, we found more participants with physical frailty than with cognitive frailty. The individuals with cognitive frailty had the highest risks of IADL limitations. Future investigation is necessary to determine whether this population is at increased risk for incidence of disability or mortality.