Δ9-Tetrahydrocannabinol: Dose-Related Effects on Timing Behavior in Chimpanzee
Δ9-Tetrahydrocannabinol: Dose-Related Effects on Timing Behavior in Chimpanzee
复制标题
Δ9-四氢大麻酚：对黑猩猩计时行为的剂量相关影响
作者：
D. Conrad;T. Elsmore;F. J. Sodetz
将对人类有效范围内的剂量的Δ9-四氢大麻酚经口给予黑猩猩，通过食物强化的多链接链式时间表维持稳定、有效的计时性能。增强随着剂量的增加而减少，因为总操作性计时反应的频率降低，计时性能的准确性降低。更高剂量的影响长达3天。
Δ9-Tetrahydrocannabinol, at doses within the effective range for humans, was administered orally to chimpanzees with stable, efficient timing performances maintained by multilink chained schedules of food reinforcement. Reinforcements decreased with increasing dose, because of decreased frequencies of total operant timing responses and decreased accuracy of the timing performances which did occur. Higher doses exerted an effect for up to 3 days.