Pressor Responses to Noxious Stimuli in Hypertensive Patients: Effects of Reserpine and Chlorothiazide
Pressor Responses to Noxious Stimuli in Hypertensive Patients: Effects of Reserpine and Chlorothiazide
复制标题
高血压患者对有害刺激的升压反应：利血平和氯噻嗪的作用
作者：
A. P. Shapiro
在接受利血平和氯噻嗪单独和联合治疗的高血压患者组中，测定了对三种标准化伤害性刺激的升压和脉率反应。尽管这些药物导致静息血压显著下降，但它们未能减少由身体或心理刺激引起的血压和心率升高的实际幅度。可能的生理解释和这些数据的治疗意义已被指出。
The pressor and pulse rate responses to three standardized noxious stimuli were determined in groups of hypertensive patients receiving reserpine and chlorothiazide, alone and in combination. Although the drugs caused a significant decline in resting blood pressure, they failed to diminish the actual magnitude of the elevations in pressure and heart rate resulting from either physical or psychological stimuli. The possible physiological interpretations and the therapeutic implications of these data have been pointed out.