Effect of heme on the activity of chick embryo liver mitochondrial δ‐aminolevulinate synthase
Effect of heme on the activity of chick embryo liver mitochondrial δ‐aminolevulinate synthase
复制标题
血红素对鸡胚肝线粒体δ-氨基乙酰丙酸合酶活性的影响
DOI：
10.1016/0014-5793(84)80099-x
复制
发表时间：
1984
期刊：
影响因子：
3.5
通讯作者：
W. H. Elliott
中科院分区：
文献类型：
--
作者：
B. Pirola;G. Srivastava;I. Borthwick;J. Brooker;B. May;W. H. Elliott
我们研究了血红素对从药物诱导的鸡胚肝线粒体中分离的天然δ-氨基酮戊酸合成酶活性的影响。该酶不受浓度高达1 nM的血红素的抑制，并且这一发现使得血红素不可能在生理上控制线粒体δ-氨基乙酰丙酸合酶活性。
We have examined the effect of heme on the activity of native δ-aminolevulinate synthase isolated from drug-induced chick embryo liver mitochondria. The enzyme was not inhibited by concentrations of heme up to 1nM and this finding makes it improbable that heme acts physiologically to control mitochondrial δ-aminolevulinate synthase activity.