Analysis of a chemotaxis-convection model of capillary-sprout growth during tumor angiogenesis

Analysis of a chemotaxis-convection model of capillary-sprout growth during tumor angiogenesis
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DOI:
10.1016/j.jmaa.2019.123474
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发表时间:
2020-01
影响因子:
1.3
通讯作者:
Genglin Li;Youshan Tao
Genglin Li;Youshan Tao
中科院分区:
数学3区
文献类型:
--
作者:
Genglin Li;Youshan Tao

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在有界的真实的区间内,本文考虑了描述血管新生过程中毛细血管芽分支的趋化-对流模型{ut = d 1 u x x−(u v x)x+(u w x)x,v t= d 2 v x x+(v w x)x+ k u− μ v,w t= d 3 w x+ r u− δ w,其中d 1,d 2,d 3,k,r,μ和δ为正参数。它表明,对于所有适当的正则初始数据,相关的Neumann初边值问题承认一个全局定义的有界光滑解。
In a bounded real interval, this work considers the chemotaxis-convection model {u t= d 1 u x x−(u v x) x+(u w x) x, v t= d 2 v x x+(v w x) x+ k u− μ v, w t= d 3 w x x+ r u− δ w, that describes the branching of capillary sprouts during angiogenesis, where d 1, d 2, d 3, k, r, μ and δ are positive parameters. It is shown that for all suitably regular initial data, an associated Neumann initial-boundary problem admits a globally defined bounded smooth solution.