Superoxide generation by hypodense eosinophils from patients with asthma.

Superoxide generation by hypodense eosinophils from patients with asthma.
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哮喘患者的低密度嗜酸性粒细胞产生超氧化物。

DOI:
10.1164/ajrccm/142.1.120
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发表时间:
1990
期刊:
The American review of respiratory disease
影响因子:
--
通讯作者:
Busse,WW
Busse,WW
中科院分区:
--
文献类型:
--
作者:
Sedgwick,JB;Geiger,KM;Busse,WW

文献摘要

被引文献

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为了进一步表征低密度嗜酸性粒细胞的功能特性,我们从哮喘患者的外周血中分离纯化的低密度嗜酸性粒细胞群体,并将其超氧化物(02)的生成与来自同一患者和对照组的其他粒细胞群体进行比较。由于许多原因,我们选择测量氧化产物的产生作为嗜酸性粒细胞功能的标志。
To further characterize the functional properties of low-densityeosinophils, we isolated purified populations of hypodense eosinophils from the peripheral blood of patients with asthma and compared their generation of superoxide (02) with other granulocyte populations from the same patients and control subjects. For a number of reasons, we elected to measure the generation of oxidative products as a marker of eosinophil function.