OPTN/SRTR 2016 Annual Data Report: Lung

OPTN/SRTR 2016 Annual Data Report: Lung
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DOI:
10.1111/ajt.14562
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发表时间:
2018-01-01
影响因子:
8.8
通讯作者:
Kasiske, B. L.
Kasiske, B. L.
中科院分区:
医学2区
文献类型:
--
作者:
Valapour, M.;Lehr, C. J.;Kasiske, B. L.

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2016年,2692名年龄在12岁或以上的候选人被添加到肺移植等待名单中;进行了2345例移植手术,这是以往任何一年的最大数量。2016年名单候选人的轮候时间中位数为2.5个月,D组候选人的轮候时间最短。2016年,移植率增加到每100等待名单年191.9例移植,等待名单死亡率略有下降,每100等待名单年15.1例死亡。短期生存率持续改善,2015年接受者的6个月死亡率为6.6%,1年死亡率为10.8%,而2014年接受者分别为8.0%和13.3%。长期生存率保持不变; 55.6%的受者在5年时存活。2016年,23名0-11岁的新候选人被添加到等待名单中,并进行了16例肺移植手术。2014-2015年接受移植的0-11岁肺移植受者的移植后死亡率在6个月时为13.8%,在1年时为19.6%。在2015年实施修订后的肺分配评分后,等待名单和移植人口统计学特征的变化继续发展。可能归因于修订后的LAS的一些早期趋势是更短的等待时间,D组移植候选人的数量稳定,以及LAS与极高分数的较低患病率的趋同。
In 2016, 2692 candidates aged 12 years or older were added to the lung transplant waiting list; 2345 transplants were performed, the largest number of any prior year. The median waiting time for listed candidates in 2016 was 2.5 months, and waiting times were shortest for group D candidates. The transplant rate increased to 191.9 transplants per 100 waitlist years in 2016, with a slight decrease in waitlist mortality to 15.1 deaths per 100 waitlist years. Short-term survival continued to improve, with a 6-month death rate of 6.6% and a 1-year death rate of 10.8% among recipients in 2015 compared with 8.0% and 13.3%, respectively, among recipients in 2014. Long-term survival rates remained unchanged; 55.6% of recipients were alive at 5 years. In 2016, 23 new candidates aged 0-11 years were added to the waiting list and 16 lung transplants were performed. Incidence of posttransplant mortality for lung transplant recipients aged 0-11 years who underwent transplant in 2014-2015 was 13.8% at 6 months and 19.6% at 1 year. Changes in waitlist and transplant demographic features continued to evolve following implementation of the revised lung allocation score in 2015. Some early trends that may be attributable to the revised LAS are shorter waiting times, stabilization of the number of group D candidates listed for transplant, and convergence of LAS with lower prevalence of extremely high scores.