Dietary α-ketoglutarate supplementation improves hepatic and intestinal energy status and anti-oxidative capacity of Cherry Valley ducks
Dietary α-ketoglutarate supplementation improves hepatic and intestinal energy status and anti-oxidative capacity of Cherry Valley ducks
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DOI：
10.1111/asj.12824
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发表时间：
2017-11-01
影响因子：
2
通讯作者：
Ding, Binying
中科院分区：
文献类型：
--
作者：
Guo, Shuangshuang;Duan, Rui;Ding, Binying
α-酮戊二酸（AKG）是人类和动物营养中广泛使用的膳食补充剂。本试验旨在研究日粮中添加AKG对樱桃谷肉鸭能量状况及肝脏和肠黏膜抗氧化能力的影响。试验选用1日龄肉鸭80只，随机分为4组，分别在基础日粮中添加0%（对照）、0.5%、1.0%和1.5%的AKG。不同剂量的AKG可线性降低肝脏中一磷酸腺苷（AMP）与三磷酸腺苷（ATP）的比值，但增加ATP含量和腺苷酸能荷（AEC），分别呈二次曲线和线性曲线（P
alpha-Ketoglutarate (AKG) is an extensively used dietary supplement in human and animal nutrition. The aim of the present study was to investigate effects of dietary AKG supplementation on the energy status and anti-oxidative capacity in liver and intestinal mucosa of Cherry Valley ducks. A total of 80 1-day-old ducks were randomly assigned into four groups, in which ducks were fed basal diets supplemented with 0% (control), 0.5%, 1.0% and 1.5% AKG, respectively. Graded doses of AKG supplementation linearly decreased the ratio of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) in the liver, but increased ATP content and adenylate energy charge (AEC) in a quadratic and linear manner, respectively (P