Creating biological nanomaterials using synthetic biology.

Creating biological nanomaterials using synthetic biology.
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DOI:
10.1088/1468-6996/15/1/014401
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发表时间:
2014-02
影响因子:
5.5
通讯作者:
Ruder WC
Ruder WC
中科院分区:
材料科学2区
文献类型:
--
作者:
Rice MK;Ruder WC

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合成生物学是一门结合科学和工程方法来精确控制生物网络的新学科。这些信令网络在生物医学和生化工程等领域尤为重要。此外,生物网络对自然产生的生物纳米材料的生产也是至关重要的,因此,合成生物学在创造新材料方面具有巨大的潜力。本文介绍了合成生物学领域,讨论了生物系统如何自然产生材料,然后给出了将合成生物学方法结合到新材料开发中的例子和策略。特别是,讨论了利用合成生物学来生产有机和无机纳米材料的策略。最终,合成生物学有可能极大地影响生物材料科学,在医疗系统中具有重要的潜在应用。
Synthetic biology is a new discipline that combines science and engineering approaches to precisely control biological networks. These signaling networks are especially important in fields such as biomedicine and biochemical engineering. Additionally, biological networks can also be critical to the production of naturally occurring biological nanomaterials, and as a result, synthetic biology holds tremendous potential in creating new materials. This review introduces the field of synthetic biology, discusses how biological systems naturally produce materials, and then presents examples and strategies for incorporating synthetic biology approaches in the development of new materials. In particular, strategies for using synthetic biology to produce both organic and inorganic nanomaterials are discussed. Ultimately, synthetic biology holds the potential to dramatically impact biological materials science with significant potential applications in medical systems.
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