Effects of training on reproductive tissue blood flow in exercising pregnant rats.
Effects of training on reproductive tissue blood flow in exercising pregnant rats.
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训练对运动怀孕大鼠生殖组织血流的影响。
DOI：
10.1152/jappl.1990.69.6.2097
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Armstrong,RB
中科院分区：
文献类型：
--
作者：
Jones,MT;Norton,KI;Dengel,DR;Armstrong,RB
本研究的目的是探讨1）跑台训练是否会减轻妊娠大鼠在急性次极量运动（EX）期间发生的生殖（RBF）和内脏组织血流量（VBF）的减少; 2）训练是否会影响胎仔数/胎仔体重。一组（T）雌性大鼠在怀孕前在跑步机上训练（10度倾斜，30 m/min），1 h/天，5天/周，持续10周。第二组（UT）以同样的速度和坡度跑10 min/d，5 d/wk，共2 wk。将T和UT大鼠饲养至妊娠。在EX前和EX的1和10分钟（10度倾斜，30 m/min）测量骨骼肌血流量、RBF和VBF。在运动前或运动中，两组之间的RBF和VBF、心率或平均动脉压均无差异。从EX前到EX，两组的VBF（肝脏除外）和RBF均降低。在大多数肌肉骨骼肌血流量增加两组从前EX到EX。两组的平均动脉压从EX前到EX都没有变化，但两组的心率都显著增加。未观察到组间胎仔数量、胎仔体重或胎仔吸收存在差异。得出的结论是，培训并没有显着减弱的RBF和VBF在怀孕的大鼠，发生在急性发作的次最大EX和培训不影响胎儿体重或胎儿数量的减少。
The purpose of this study were to investigate 1) whether treadmill training would attenuate the reduction in reproductive (RBF) and visceral tissue blood flow (VBF) that occurs during an acute bout of submaximal exercise (EX) in pregnant rats and 2) whether fetal number of fetal weight would be affected by training. One group (T) of female rats trained on a treadmill (10 degrees incline, 30 m/min) for 1 h/day 5 days/wk for 10 wk before becoming pregnant. A second group (UT) was run at the same speed and incline for 10 min/day 5 days/wk for 2 wk. T and UT rats were bred until pregnant. Skeletal muscle blood flow, RBF, and VBF were measured at pre-EX and at 1 and 10 min of EX (10 degrees incline, 30 m/min). No differences were observed before or during exercise between the two groups in RBF and VBF, heart rate, or mean arterial pressure. Both groups experienced decreases in VBF (except liver) and RBF from pre-EX to EX. In most muscles skeletal muscle blood flow increased for both groups from pre-EX to EX. Neither group experienced a change in mean arterial pressure from pre-EX to EX, but heart rate increased significantly for both groups. No differences were observed between groups in fetal number, fetal weight, or fetal resorptions. It was concluded that training does not significantly attenuate the reduction in RBF and VBF in pregnant rats that occurs during an acute bout of submaximal EX and that training does not affect fetal weight or fetal number.