[Localization of lesions in aphasia--clinical-CT scan correlations (Part III): Paraphasia and meaningless speech].
[Localization of lesions in aphasia--clinical-CT scan correlations (Part III): Paraphasia and meaningless speech].
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失语症病变定位——临床-CT扫描相关性（第三部分）：失语症与无意义言语]。
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
H. Metoki
中科院分区：
文献类型：
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作者：
K. Hojo;S. Watanabe;H. Tasaki;T. Sato;H. Metoki
根据100幅真实图片的视觉命名任务结果，从450例不同类型的失语症患者中筛选出51例，分为无意义言语组和错语组。随后，在对自发言语和命名任务进行定量和定性评价的基础上，将两组被试分为无意义言语组（RU组）、未分化行话组（UJ组）、无语义行话组（AJ组）和错语组（LP组、VP组）。使用微型计算机，病变的部位和范围，如由计算机断层扫描显示的每组被叠加到标准化矩阵。研究了病灶和病变范围与各组之间的关系。RU组（n = 8）：该组病变体积很大，几乎所有患者均累及额颞顶叶。病变主要集中在额叶皮质、豆状核及深部结构。UJ组（n = 9）：病变体积大，累及多位于豆状核、岛盖、颞中、上级及缘上回。由于病变模式的变异性很大，它已被证明几乎没有定位价值。AJ组（n = 11）：病灶大小明显小于其他组。至少80%的患者有涉及Wernick区的上级颞叶病变和缘上回的皮质下病变。LP组（n = 8）：病变相对较大。虽然有一些集中的病变在豆状核区，后部的小脑和颞前回，这是很难定位在一个明确的区域。VP组（n = 15）：病变较LP组稍小，位置稍深。这一发现已被证明没有什么本地化价值。
According to the result of the visual naming task of 100 realistic pictures, 51 cases were selected from 450 cases with various types of aphasia and divided into two groups, namely, meaningless speech group and paraphasic group. Subsequently, on the basis of the quantitative and qualitative valuation of the spontaneous speech and the naming task, the two groups were subdivided with meaningless speech group being recurring utterance (RU group), undifferentiated jargon (UJ group), asemantic jargon (AJ group) and paraphasic group being literal paraphasia (LP group), verbal paraphasia (VP group). Using a microcomputer, the locus and extent of the lesions, as demonstrated by computed tomography for each group were superimposed onto standardized matrices. The relationship between the focus and the extent of the lesions and the various groups was investigated. RU group (n = 8): The size of the lesions of this group was very large and almost all patients had extensive lesions involving frontal-temporal-parietal lobes. There was marked concentration of the lesions in the area of the insula, lenticular nucleus and the deep structures of the frontal lobe. UJ group (n = 9): In general, the size of the lesions was large and highly involved lesions were located in the lenticular nucleus and operculum as well as the superior and middle temporal gyri and the supramarginal gyrus. Because of the large variability in lesion patterns, it has proved to have little localizing value. AJ group (n = 11): The size of the lesions was significantly smaller than any other group. At least 80% of the patients had the superior temporal lesions involving Wernick's area and subcortical lesions of the supramarginal gyrus. LP group (n = 8): The lesions were relatively large in size. While there was some concentration of the lesions in the area of the lenticular nucleus, posterior parts of the insula and anterior temporal gyrus, it was difficult to localize in a definite region. VP group (n = 15): The lesions of this group were a little smaller and located slightly deeper than those of the LP group. The finding has proved to have little localizing value.