Effect of covert nutritive dilution on the spontaneous food intake of obese individuals: a pilot study.
Effect of covert nutritive dilution on the spontaneous food intake of obese individuals: a pilot study.
复制标题
隐蔽营养稀释对肥胖个体自发食物摄入的影响：一项试点研究。
DOI：
--
复制
发表时间：
1977
影响因子：
7.1
通讯作者：
T. Van Itallie
中科院分区：
文献类型：
--
作者：
K. Porikos;G. Booth;T. Van Itallie
本研究探讨了一种新的实验方法的可行性，以研究隐性营养稀释对肥胖个体自发食物摄入的影响。研究人员对8名肥胖患者进行了为期15天的住院治疗，在此期间，他们没有意识到自己的食物摄入受到了监控。拼盘式的食物呈现方式鼓励随意进食。热量稀释是通过在正常饮食中用含阿斯巴甜的类似物代替含蔗糖的产品来实现的。在基线期，受试者自发进食足够的常规食物以维持体重，甚至轻微增加体重。用含阿斯巴甜的产品代替含蔗糖的产品可以立即减少大约25%的自发能量摄入。阿斯巴甜类似物和它们的传统对应物一样被接受，这一点可以从每一种的消费量上看出来。这些初步结果表明，在代谢病房的环境下，有可能将肥胖个体的自发食物摄入量维持在足以维持体重的水平，并通过隐蔽地改变饮食的热量密度，任意地将这些摄入水平降低25%或更多。
The present study investigated the feasibility of a new experimental approach for studying the effect of covert nutritive dilution on the spontaneous food intake of obese individuals. Eight obese subjects were studied as inpatients on a metabolic unit for 15 days during which time they were unaware that their food intake was being monitored. A platter method of food presentation encouraged ad libitum ingestion. Caloric dilution was achieved by replacing sucrose-containing products with aspartame-sweetened analogues in an otherwise normal diet. During the base-line period the subjects spontaneously ate sufficient conventional food to maintain or even slightly increase body weight. Covert substitution of aspartame-sweetened products for their sucrose counterparts resulted in an immediate reduction in spontaneous energy intake of approximately 25%. The aspartame analogues were as well accepted as their conventional counterparts, as indicated by the equal quantity of each consumed. These preliminary results demonstrate that, in a metabolic ward setting, it is possible to maintain the spontaneous food intake of obese individuals at levels sufficient to preserve body weight and arbitrarily to decrease those levels of intake by 25% or more through covert changes in the caloric density of the diet.