Gait speed and overactive bladder in the healthy community-dwelling super elderly: The Sukagawa Study
Gait speed and overactive bladder in the healthy community-dwelling super elderly: The Sukagawa Study
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DOI：
10.1002/nau.24148
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发表时间：
2019-08-22
影响因子：
2
通讯作者：
Fukuhara, Shunichi
中科院分区：
文献类型：
--
作者：
Omae, Kenji;Yamamoto, Yosuke;Fukuhara, Shunichi
目的本研究的目的是评估肌肉质量，握力和步态速度与膀胱过度活动症（OAB）在社区居住的老年人。方法本横断面研究的数据来自Sukagawa研究的350名75岁或以上的日本健康社区居住老年人。通过生物电阻抗测量肌肉质量（kg），而通过性能测试测量握力（kg）和步态速度（m/s）。根据体重指数（BMI）校正肌肉质量和握力。主要结局是OAB的存在，使用OAB症状评分进行评估。结果在分析的314名参与者中，146名（47%）为男性，88名（28%）患有OAB。平均（SD）BMI、肌肉质量、握力和步态速度分别为23.2（3.2）kg/m2、38.4（7.5）kg、26.6（8.1）kg和1.2（0.2）m/s。多变量逻辑回归分析显示，较慢的步态速度与OAB的可能性更大相关（每-1 SD的校正比值比[aOR]，1.47; 95%置信区间[CI]，1.11-1.95）。未观察到肌肉质量或握力与OAB之间存在显著相关性（aOR每-1 SD，分别为0.75，1.03; 95% CI，0.41-1.37，0.62-1.72）。步态速度较慢也与尿急和急迫性尿失禁的可能性较高相关（aOR/-1 SD，分别为1.35，1.40; 95% CI，1.04-1.74，1.06-1.84）。结论在健康的社区老年人中，步态速度与OAB（包括急迫性和急迫性尿失禁）相关。我们的研究结果可能会提供一个新的框架OAB管理方面的功能性流动。
Aim The objective of this study is to assess the association of muscle mass, grip strength, and gait speed with overactive bladder (OAB) in community-dwelling elderly adults. Methods This cross-sectional study was based on the data collected from 350 Japanese healthy community-dwelling elderly individuals aged 75 years or older from the Sukagawa Study. Muscle mass (kg) was measured by bioelectrical impedance, whereas grip strength (kg) and gait speed (m/s) were measured by performance testing. Muscle mass and grip strength were corrected for body mass index (BMI). The primary outcome was the presence of OAB, evaluated using the OAB symptom score. Results Of the 314 participants analyzed, 146 (47%) were men and 88 (28%) presented with OAB. The mean (SD) BMI, muscle mass, grip strength, and gait speed were 23.2 (3.2) kg/m(2), 38.4 (7.5) kg, 26.6 (8.1) kg, and 1.2 (0.2) m/s, respectively. Multivariable logistic regression analysis revealed that slower gait speed was associated with a greater likelihood of OAB (adjusted odds ratio [aOR] per -1 SD, 1.47; 95% confidence interval [CI], 1.11-1.95). No significant associations between muscle mass or grip strength and OAB were noted (aOR per -1 SD, 0.75, 1.03; 95% CI, 0.41-1.37, 0.62-1.72, respectively). Slower gait speed was also associated with higher likelihood of urgency and urgency incontinence (aOR per -1 SD, 1.35, 1.40; 95% CI, 1.04-1.74, 1.06-1.84, respectively). Conclusions In the healthy community-dwelling elderly, gait speed was associated with OAB, including urgency and urgency incontinence. Our findings may provide a new framework for OAB management with respect to functional mobility.