FATNESS, FAT DISTRIBUTION, AND GLUCOSE-TOLERANCE IN 2ND-GENERATION JAPANESE-AMERICAN (NISEI) MEN
FATNESS, FAT DISTRIBUTION, AND GLUCOSE-TOLERANCE IN 2ND-GENERATION JAPANESE-AMERICAN (NISEI) MEN
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DOI：
10.1093/ajcn/50.1.9
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发表时间：
1989-07-01
影响因子：
7.1
通讯作者：
FUJIMOTO, WY
中科院分区：
文献类型：
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作者：
NEWELLMORRIS, LL;TREDER, RP;FUJIMOTO, WY
研究人员对229名第二代日裔美国男性的脂肪量和分布与葡萄糖耐量之间的关系进行了研究。根据75 g口服糖耐量试验结果和世界卫生组织（WHO）诊断标准，79名男性正常，72名糖耐量（IGT）受损，78名患有非胰岛素依赖型糖尿病。诊断组通过10项肥胖指标进行比较，这些指标来自体重指数、皮肤褶厚度和脂肪面积，这些指标由计算机断层扫描确定。在五个指标上，IGT男性比正常男性胖；糖尿病男性有4例肥胖，组间差异有统计学意义（p .gtoreq）。0.03)。糖尿病患者肩胛下脂肪沉积最多（p = 0.01），肱二头肌脂肪多于正常男性（p = 0.01）；IGT患者大腿中部脂肪含量高于糖尿病患者（p = 0.01）。糖尿病组和IGT组腹部脂肪较多（p = 0.003）。对于血清葡萄糖水平，体重指数和肩胛下脂肪之间存在相互作用。
The association between amount and distribution of fat and glucose tolerance was examined in 229 second-generation Japanese-American men. According to the results of a 75-g oral glucose tolerance test and by World Health Organization (WHO) diagnostic criteria, 79 men were normal, 72 had impaired glucose tolerance (IGT), and 78 had noninsulin-dependent diabetes mellitus. Diagnostic groups were compared by using 10 measures of fatness derived from body mass indices, skinfold thicknesses, and fat areas, which were determined by computed tomography. IGT men were fatter than normal men on five measures; diabetic men were fatter on four and group differences were marginally significant (p .gtoreq. 0.03). Diabetic subjects had the largest deposits of subscapular (p = 0.01) and more biceps fat than normal men (p = 0.01); IGT men had more midthigh fat than diabetic men (p = 0.01). The diabetes and IGT groups possessed more intraabdominal fat (p = 0.003). For serum glucose levels there was an interaction between body mass index and subscapular fat.