Prevalence of human T cell lymphotropic virus (HTLV) types I and II and human immunodeficiency virus type 1 infections among persons with Hansen's disease in New York City.
Prevalence of human T cell lymphotropic virus (HTLV) types I and II and human immunodeficiency virus type 1 infections among persons with Hansen's disease in New York City.
复制标题
纽约市汉森病患者中人类 T 细胞淋巴细胞病毒 (HTLV) I 型和 II 型以及人类免疫缺陷病毒 1 型感染的患病率。
DOI：
10.1093/infdis/170.4.1007
复制
发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Poiesz,BJ
中科院分区：
文献类型：
--
作者：
Glaser,JB;Levis,WR;Gruber,T;Cabrera,A;Poiesz,BJ
从 1990 年 11 月到 1991 年 6 月，连续一百七名在纽约汉森病诊所就诊的患者接受了逆转录病毒检测。该队列包括 58 名在艾滋病流行后被诊断患有汉森氏病的患者，其中 54 人在诊断出汉森氏病之前移民到美国（中位时间为 7 年）。人类T细胞淋巴细胞病毒（HTLV）I型感染总体率（1.9%）较低。 55 名加勒比出生的患者中，有 2 名 (3.6%) 患有聚合酶链反应 (PCR) 记录的 HTLV-I 感染，但在没有汉森病的人群中，这一发病率并不高于预期。没有患者有 HTLV-II 或人类免疫缺陷病毒 (HIV) 1 型感染的 PerR 记录证据。研究对象中 HIV-1 感染率较低可能与缺乏典型的 HIV 危险行为有关，因为大约一半的研究对象可能在感染 HIV-1 的同时长期培养麻风分枝杆菌。
One-hundred seven consecutive patients attending a New York Hansen‘s disease clinic from November 1990 through June 1991 were tested for retroviruses. This cohort included 58 patients diagnosed with Hansen’s disease after the onset of the AIDS epidemic, 54 of whom immigrated to the United States before diagnosis of Hansen‘s disease (median, 7 years). The overall rate (1.9%) of human T celllymphotropic virus (HTLV) type I infection was low. Two (3.6%) of 55 Caribbean-born patients had polymerase chain reaction (PCR)-documented HTLV-I infection, but this incidence was not higher than expected in persons without Hansen’s disease. No patient had PeR-documented evidence of either HTLV-II or human immunodeficiency virus (HIV) type 1 infection. The low rate of HIV-1 among those studied was likely related to an absence of classic HIV risk behavior because about half of the cohort could have incubatedMycobacterium lepraefor a prolonged period while infected with HIV-1.