Binge alcohol and HIV: leaky gut and neurodegeneration through the gut–brain axis
Binge alcohol and HIV: leaky gut and neurodegeneration through the gut–brain axis
复制标题
酗酒和艾滋病毒：肠漏和肠脑轴神经变性
DOI：
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
Sulie L. Chang
中科院分区：
文献类型：
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作者：
M. Essa;B. Song;Sulie L. Chang
目前，美国约有120万人，全球约有3670万人[1，2]感染人类免疫缺陷病毒（HIV）。不幸的是，大约20%的艾滋病毒感染者不知道自己是否感染了艾滋病毒[1]，并继续吸烟、酗酒和摄入富含n-6脂肪酸的垃圾食品等不健康的生活方式。此外，酗酒现在被认为是一个主要的公共卫生问题，占美国酒精消费量的75%以上。[3]此外，酒精滥用是艾滋病毒感染者中经常观察到的各种疾病状态的主要原因[4]，因为这些艾滋病毒感染者中约有50%经常沉迷于酗酒。[五]《中国日报》
Currently, approximately 1.2 million people in the United States and 36.7 million individuals globally[1,2] are living with human immunodeficiency virus (HIV) infection. Unfortunately, around 20% of HIV-infected people do not know whether they are infected with HIV[1] and continue unhealthy lifestyles of tobacco smoking, binge alcohol drinking, and intake of n-6 fatty acid-rich junk foods. In addition, binge drinking is now considered as a major public health problem and accounts for more than 75% of alcohol consumed in the United States.[3] Furthermore, alcohol abuse is a major cause of various disease states frequently observed in HIV-infected people[4] as approximately 50% of these HIV-infected people often indulge in binge drinking.[5]