LIMITED EFFICACY OF LEUKOPOOR PLATELETS FOR PREVENTION OF FEBRILE TRANSFUSION REACTIONS
LIMITED EFFICACY OF LEUKOPOOR PLATELETS FOR PREVENTION OF FEBRILE TRANSFUSION REACTIONS
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DOI：
10.1093/ajcp/95.5.733
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发表时间：
1991-05-01
影响因子：
3.5
通讯作者：
KRUSKALL, MS
中科院分区：
文献类型：
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作者：
MANGANO, MM;CHAMBERS, LA;KRUSKALL, MS
贫白细胞红细胞成分可降低发热性输血反应的发生率。 对白细胞减少的血小板的类似疗效尚未令人信服地确定。 作者分析了36例患者（26名女性，10名男性）的输血记录，这些患者在对未修饰血小板发生发热反应后接受了白细胞减少血小板。 这些患者接受了409次未经修饰的输血（平均/患者11），发生了84例发热反应（发生率20.5%）。 对未修饰的、非HLA匹配的单个供体血小板（14.0%）和HLA匹配的血小板（6.5%）的反应率显著低于对混合浓缩物（27.2%）的反应率（P
Leukopoor red cell components have a reduced incidence of febrile transfusion reactions. An analogous efficacy for leukopoor platelets has not been convincingly established. The authors analyzed the transfusion records of 36 patients (26 women, 10 men) who received leukopoor platelets following febrile reactions to unmodified platelets. These patients received 409 unmodified transfusions (mean/patient 11) with 84 febrile reactions (rate 20.5%). Reaction rates to unmodified, non-HLA-matched single donor platelets (14.0%) and HLA-matched platelets (6.5%) were significantly lower than to pooled concentrates (27.2%) (P