Influence of flow variations on capillary hematocrit in mesentery.
Influence of flow variations on capillary hematocrit in mesentery.
复制标题
流量变化对肠系膜毛细血管血细胞比容的影响。
DOI：
10.1152/ajplegacy.1971.221.1.105
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发表时间：
1971
期刊：
影响因子：
--
通讯作者：
J. H. Dial
中科院分区：
文献类型：
--
作者：
P. Johnson;J. Blaschke;K. S. Burton;J. H. Dial
保罗·约翰逊，肯尼思·琼·布拉斯科伯顿，乔H。Jzozo变异对Mcsenter-y毛细血管红细胞压积的影响。Am. J.Physiol.221（1）：105- 112。1971.~通过计数通过毛细血管的红细胞并同时测量红细胞速度，在线测量猫肠系膜毛细血管中的红细胞间距。在控制条件下，大多数毛细血管的红细胞压积值相当稳定，尽管有些毛细血管显示出不稳定的变化，在少数毛细血管中，明确的周期性是明显的。通过动脉灌注回路的部分闭塞，肠系膜的总流量减少1 -2分钟。毛细血管红细胞压积是，平均而言，在低血压期间不变，虽然三分之一的毛细血管表现出可重复的增加或减少。这些变化比伴随的压力和流量降低要慢。随着压力和流量的突然恢复，红细胞压积基本保持不变。在某些情况下，血管舒缩导致红细胞压积的变化。这似乎与毛细血管前括约肌或可能的小动脉的血管运动有关。我们的研究结果是一致的假设，即在毛细血管入口处的流量分馏是一个重要的决定因素毛细血管血细胞比容，而绝对流量似乎没有什么影响。
JOHNSON, PAUL C.,JON BLASCHKE, KENNETH S. BURTON, AND JOE H. DIAL. Infruence of Jzozo variations on capillary hematocrit in mcsenter-y. Am. J. Physiol. 221(l): 105-l 12. 1971.~Red cell spacing was measured on line in mesenteric capillaries of the cat by counting red cells passing through the capillary and simultaneously measuring red cell velocity. Most capillaries had reasonably stable hematocrit values under control conditions although some showed erratic changes and in a few a well-defined periodicity was apparent. Gross flow to the mesentery was reduced for l-2 min by partial occlusion of the arterial perfusion circuit. Capillary hematocrit was, on the average, unchanged during hypotension although onethird of the capillaries showed a reproducible increase or decrease. These changes were slower than the accompanying reduction of pressure and flow. With sudden restoration of pressure and flow, hematocrit remained essentially unchanged. Vasomotion led in some instances to changes in hematocrit. This appeared to be associated with vasomotion of precapillary sphincters or possibly metarterioles. Our findings are consistent with the hypothesis that flow fractionation at the capillary entrance is an important determinant of capillary hematocrit while the absolute flow rate seems to have little effect.