Treatment of psoriasis with crisaborole
Treatment of psoriasis with crisaborole
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DOI：
10.1080/09546634.2018.1480747
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发表时间：
2018-06
影响因子：
2.9
通讯作者：
Erica B. Lee;M. Lebwohl;Jashin J. Wu
中科院分区：
文献类型：
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作者：
Erica B. Lee;M. Lebwohl;Jashin J. Wu
克里沙硼是一种局部应用的磷酸二酯酶-4（PDE 4）抑制剂，对特应性皮炎患者有效。由于全身性PDE 4抑制剂也已成功用于银屑病，因此正在进行临床试验以确定局部PDE 4抑制剂在这些患者中的效用。然而，目前没有文献记录使用阿托硼洛治疗银屑病。在这里，我们提出了两个案例中，银屑病患者成功地治疗与阿托硼洛。
Abstract Crisaborole, a topical phosphodiesterase-4 (PDE4) inhibitor, is effective in patients with atopic dermatitis. As systemic PDE4 inhibition has also been used with success in psoriasis, clinical trials are underway to determine the utility of topical PDE4 inhibitors in these patients. However, there is no current literature documenting use of crisaborole for psoriasis. Here, we present two cases in which patients with psoriasis were treated successfully with crisaborole.