Multivitamin-multimineral supplements' effect on total nutrient intake.
Multivitamin-multimineral supplements' effect on total nutrient intake.
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DOI：
10.1093/ajcn/85.1.280s
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发表时间：
2007-01
期刊：
影响因子：
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通讯作者：
S. Murphy;K. White;S. Park;Sangita Sharma
中科院分区：
文献类型：
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作者：
S. Murphy;K. White;S. Park;Sangita Sharma
多种维生素-多种矿物质补充剂的使用很普遍，可以大大增加总营养素的摄入量。在夏威夷-洛杉矶多种族队列（MEC）中，48%的男性和56%的无慢性病女性报告在过去一年中至少每周使用多种维生素补充剂。我们根据1993-1996年对MEC参与者进行的自填定量食物频率问卷调查，计算了17种营养素的营养充足率。虽然仅从食物中获得营养充足的患病率在多种维生素补充剂使用者中（n = 21，056）高于非使用者（n = 69，715），但平均差异仅为2个百分点。对于复合维生素使用者，当包括补充剂的摄入量时，男性和女性的充足率平均提高了8个百分点。使用者也更有可能有潜在的过量摄入，特别是铁，锌，维生素A和烟酸。夏威夷的26,735名MEC参与者在1999-2001年回答了一个关于多种维生素使用的开放性问题，报告使用了1246种不同的产品。这些产品的营养成分差异很大，对于某些营养素，第90百分位数的产品成分比中位数的成分高10倍。我们的结论是，补充剂用户的营养充足性和过剩的分析应扩展到国家样本和实际使用的补充剂的组成数据是最好的假设一个默认的营养配置文件的复合维生素补充剂。复合维生素产品可以更好地制定，以减少不足的流行，并减少过量摄入的风险。
Use of multivitamin-multimineral supplements is widespread and can contribute substantially to total nutrient intakes. In the Hawaii-Los Angeles Multiethnic Cohort (MEC), 48% of men and 56% of women without chronic diseases reported use of multivitamin supplements at least weekly over the past year. We calculated the prevalence of nutrient adequacy for 17 nutrients based on responses to a self-administered quantitative food-frequency questionnaire administered to MEC participants at baseline in 1993-1996. Although the prevalence of nutrient adequacy from food only was higher for multivitamin supplement users (n = 21,056) than for nonusers (n = 69,715), differences averaged only 2 percentage points. For multivitamin users, the prevalence of adequacy improved by an average of 8 percentage points for both men and women when intake from supplements was included. Users were also more likely to have potentially excessive intakes, particularly for iron, zinc, vitamin A, and niacin. The 26,735 MEC participants in Hawaii who answered an open-ended question about multivitamin use in 1999-2001 reported using 1246 different products. The nutrient profile of these products varied widely, and the composition of products at the 90th percentile was 10-fold greater than the composition at the median for some nutrients. We conclude that analyses of nutrient adequacy and excess for supplement users should be extended to national samples and that composition data on actual supplements used are preferable to assuming a default nutrient profile for multivitamin supplements. Multivitamin products could be better formulated to reduce the prevalence of inadequacy and also to reduce the risk of excessive intakes.